推薦產品
化驗
>99% (TLC)
形狀
liquid
包裝
pkg of 1 × 1 mL (791640C-1mg)
製造商／商標名
Avanti Research™ - A Croda Brand 791640C
濃度
1 mg/mL (791640C-1mg)
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
15:0-18:1-d7-PG (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-[phospho-rac-(1′-glycerol)] is a deuterated phospholipid. The lipid comprises phosphatidylglycerol attached to pentadecanoic acid and oleic acid. Oleic acid harbors the deuterium ions. Phosphatidylglycerol is anionic phospholipid and is associated with thylakoids, microsomal and mitochondrial membrane.[1]
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH™ LIPIDOMIX™ Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.
應用
15:0-18:1-d7-PG (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-[phospho-rac-(1′-glycerol)] (sodium salt),) has been used:
- as a component of extraction solvent for lipid isolation from biological samples [2]
- as an internal standard to spike cell lysate and to quantify lipid species using fourier transform mass spectrometry (FTMS) analysis[3]
- as an isotopically labeled lipid internal standard for correction of lipids detected in lipid droplets using shotgun mass spectrometry analysis[4]
生化／生理作用
Phosphatidylglycerol (PG) plays a key role in photosynthesis. Cardiolipin is synthesized from PG. PG mediates many mitochondrial functions.[5]
包裝
2 mL Amber Glass Sealed Ampule (791640C-1mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC
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產品號碼
描述
訂價
訊號詞
Danger
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
標靶器官
Central nervous system, Liver,Kidney
儲存類別代碼
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
does not flash
閃點（°C）
does not flash
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Shin-Ya Morita et al.
Scientific reports, 5, 11737-11737 (2015-07-01)
Phosphatidylglycerol (PG) and cardiolipin (CL) are synthesized in mitochondria and regulate numerous biological functions. In this study, a novel fluorometric method was developed for measuring PG and CL using combinations of specific enzymes and Amplex Red. This assay quantified the
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Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using
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