跳轉至內容
Merck
全部照片(1)

文件

W329118

Sigma-Aldrich

4-羟基丁酸内酯

≥98%, FCC, FG

同義詞:

γ-丁内酯, γ-羟基丁酸内酯, 4-羟基丁酸内酯, GBL

登入查看組織和合約定價
全部照片(1)

About This Item

經驗公式（希爾表示法）:
C4H6O2
CAS號碼:
96-48-0
分子量：:
86.09
FEMA號碼:
3291
Beilstein:
105248
EC號碼:
202-509-5
歐洲委員會號碼:
615
MDL號碼:
MFCD00005386
分類程式碼代碼:
12164502
PubChem物質ID:
24901615
Flavis號碼:
10.006
NACRES:
NA.21

生物源

synthetic

品質等級

400

等級

FG
Fragrance grade
Halal
Kosher

agency

follows IFRA guidelines
meets purity specifications of JECFA

法律遵循

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FCC
FDA

蒸汽密度

3 (vs air)

蒸汽壓力

1.5 mmHg ( 20 °C)

化驗

≥98%

自燃溫度

851 °F

expl. lim.

16 %

折射率

n20/D 1.436 (lit.)

bp

204-205 °C (lit.)

mp

−45 °C (lit.)

密度

1.12 g/mL at 25 °C (lit.)

應用

flavors and fragrances

文件

see Safety & Documentation for available documents

食物過敏原

no known allergens

香料過敏原

no known allergens

感官的

caramel; creamy; fatty; oily

SMILES 字串

O=C1CCCO1

InChI

1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2

InChI 密鑰

YEJRWHAVMIAJKC-UHFFFAOYSA-N

尋找類似的產品？ 前往 產品比較指南

相關類別

應用


  • RIFM fragrance ingredient safety assessment, 4-hydroxybutanoic acid lactone, CAS Registry Number 96-48-0.: A comprehensive safety assessment of 4-hydroxybutanoic acid lactone as a fragrance ingredient, evaluating its toxicological profile and safe usage levels (Api et al., 2019).

生化／生理作用

γ-羟基丁酸(GHB)前体。 可通过阻断多巴胺能神经元的脉冲流，抑制多巴胺释放。 γ-丁内酯预处理可用于检测自身受体诱导的多巴胺释放。

相關產品

產品號碼
描述
訂價

07475

Timestrip® Food

象形圖

CorrosionExclamation mark
GHS05,GHS07

訊號詞

Danger

危險聲明

H302,H318,H336

危險分類

Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

208.4 °F - closed cup

閃點（°C）

98 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

已經擁有該產品？

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Jagan N Thupari et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(14), 9498-9502 (2002-06-13)
C75, a known inhibitor of fatty acid synthase is postulated to cause significant weight loss through decreased hypothalamic neuropeptide Y (NPY) production. Peripherally, C75, an alpha-methylene-gamma-butyrolactone, reduces adipose tissue and fatty liver, despite high levels of malonyl-CoA. To investigate this
Zheng-Yuan Su et al.
Chemical research in toxicology, 26(3), 477-485 (2013-02-28)
Cancer development has been linked to epigenetic modifications of cancer oncogenes and tumor suppressor genes; in advanced metastatic cancers, severe epigenetic modifications are present. We previously demonstrated that the progression of prostate tumors in TRAMP mice is associated with methylation
Michelle Wood et al.
Journal of chromatography. A, 1056(1-2), 83-90 (2004-12-15)
We have developed a rapid method that enables the simultaneous analysis of gamma-hydroxybutyrate (GHB) and its precursors, i.e. gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) in urine. The method comprised a simple dilution of the urine sample, followed by liquid chromatography-tandem mass
Axel Bidon-Chanal et al.
European journal of medicinal chemistry, 60, 479-489 (2013-01-29)
Glycogen synthase kinase 3β (GSK-3β) is widely recognised as a relevant player in the pathogenesis of several highly prevalent disorders such as Alzheimer's disease, mood disorders, diabetes and cancer. Therefore, this enzyme constitutes a highly attractive therapeutic target for the
Bo Xue et al.
Biochemistry, 52(13), 2359-2370 (2013-03-07)
The in vitro evolution and engineering of quorum-quenching lactonases with enhanced reactivities was achieved using a thermostable GKL enzyme as a template, yielding the E101G/R230C GKL mutant with increased catalytic activity and a broadened substrate range [Chow, J. Y., Xue
查看所有相關論文

我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務