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Merck
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重要文件

T85308

Sigma-Aldrich

三(2-氯乙基)胺 盐酸盐

98%

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About This Item

線性公式:
(ClCH2CH2)3N·HCl
CAS號碼:
分子量::
240.99
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:

品質等級

化驗

98%

mp

127-130 °C (lit.)

SMILES 字串

Cl.ClCCN(CCCl)CCCl

InChI

1S/C6H12Cl3N.ClH/c7-1-4-10(5-2-8)6-3-9;/h1-6H2;1H

InChI 密鑰

VEAUDLLZYJVHRI-UHFFFAOYSA-N

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 2 Oral - Carc. 2 - Skin Corr. 1B

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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I Sýkora et al.
Neoplasma, 28(5), 565-574 (1981-01-01)
The cytostatic TS-160 (trichloromethine hydrochloride, tris-/2-chloroethyl/amine hydrochloride) was injected subcutaneously into SPF Wistar rats of both sexes. After all doses used, spindle-cell or even polymorphocellular sarcomas developes at the injection sites in both sexes: after the dose of 0.1 mg/kg
N I Ryabchenko et al.
General physiology and biophysics, 10(1), 41-48 (1991-02-01)
The dynamic of chromatin degradation was studied in thymocytes and LS/BL tumour cells. In permeabilised LS/BL cells, the rate of DNA degradation induced by endogenous calcium and magnesium-dependent endonuclease was approx. 25 times slower than in thymocytes. In LS/BL cells
I Koza et al.
Neoplasma, 36(6), 709-718 (1989-01-01)
Fifty-three patients with advanced Hodgkin's disease, most of them previously treated, received 8 to 16 courses of modified MOPP regimens (nitrogen mustard replaced by trichlormethine in arm A, with addition of vinblastine to the 4-drug regimen in arm B, and
Landmark article Sept. 21, 1946: Nitrogen mustard therapy. Use of methyl-bis(beta-chloroethyl)amine hydrochloride and tris(beta-chloroethyl)amine hydrochloride for Hodgkin's disease, lymphosarcoma, leukemia and certain allied and miscellaneous disorders. By Louis S. Goodman, Maxwell M. Wintrobe, William Dameshek, Morton J. Goodman, Alfred Gilman and Margaret T. McLennan.
L S Goodman et al.
JAMA, 251(17), 2255-2261 (1984-05-04)
Trichloromethyl ketones as synthetically versatile donors: application in direct catalytic mannich-type reactions and the stereoselective synthesis of azetidines.
Hiroyuki Morimoto et al.
Angewandte Chemie (International ed. in English), 45(19), 3146-3150 (2006-04-06)

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