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重要文件

QBD10140

Sigma-Aldrich

Acid-dPEG®25-NHS ester

>95% (HPLC)

同義詞:

Acid-PEG-NHS ester, Acid-PEG25-NHS ester, Carboxy-PEG25-NHS ester, NHS-PEG1500-COOH, NHS-PEG25-COOH

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About This Item

經驗公式(希爾表示法):
C58H109NO31
分子量::
1316.47
MDL號碼:
分類程式碼代碼:
12352106
NACRES:
NA.22
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化驗

>95% (HPLC)

形狀

solid or viscous liquid

反應適用性

reaction type: Pegylations

聚合物結構

shape: linear
functionality: heterobifunctional

運輸包裝

ambient

儲存溫度

−20°C

SMILES 字串

N1(C(=O)CCC1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O

InChI 密鑰

XZSKTNJHWDTIJQ-UHFFFAOYSA-N

特點和優勢

Acid-dPEG25-NHS ester is an amine-reactive crosslinker designed to facilitate intermolecular crosslinking with free amines at each end of the crosslinker through a single molecular weight, discrete polyethylene glycol (dPEG) backbone. The correct use of this product eliminates intramolecular crosslinking. The dPEG backbone is amphiphilic. Consequently, it imparts water solubility to molecules to which it is conjugated. The dPEG spacer is 79 atoms (92.5 Å) long. The dPEG spacer in this product is the monodisperse PEG equivalent of PEG1000. One end of the chain terminates in a propionic acid group. The other end terminates as the N-hydroxysuccinimidyl (NHS) ester of propionic acid. While both ends of the molecule can react with free amines such as the ε-amine group of lysine, only one end of the dPEG spacer is activated as the NHS ester. This construction permits only one end of the spacer to react at a time, thus giving the user greater control over crosslinking molecules using this product.

法律資訊

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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