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LGFR100

Sigma-Aldrich

Red Fluorescent PLGA nanoparticles

100 nm average diameter

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About This Item

分類程式碼代碼:
12162002
NACRES:
NA.23
暫時無法取得訂價和供貨情況

描述

Excitation/Emission: 644/665 nm

形狀

pellets

平均直徑

100 nm

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一般說明

Particles made of poly(D,L-lactide-co-glycolide) L/G ratio of 50/50, inherent viscosity of ~0.45 dL/g.To re-constitute:
  • Warm to ambient temperature
  • Add DI water or buffer to achieve desired concentration
  • Vortex and sonicate for 5 minutes to ensure particles are well suspended

應用

Fluorescent PLGA particles for imaging and cell tracking in drug discovery. Particles can be used for fluorscent assays and drug delivery.

法律資訊

Product of Phosphorex, Inc.Degradex(RM) is a product of Phosphorex, Inc.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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文章

Polymeric antioxidants show promise in drug delivery with superior bioavailability and antioxidant potential.

Questions

1–3 of 3 Questions  
  1. is the cy5 conjugated plga?? or cy5 encapsulated plga??

    1 answer
    1. The dye is loaded inside the nanoparticles and is not covalently attached to the surface. The type of red fluorescent dye used in the manufacture of this product is not disclosed. The excitation wavelength of the dye is approximately 644 nm with an associated emission of approximately 665 nm.

      Helpful?

  2. Hello, are these nanoparticles fucnctionalized with carboxylic acids groups on the surface?

    1 answer
    1. These nanoparticles have not been functionalized beyond a red fluorescent dye.

      Helpful?

  3. Can this product be resuspended in water? What is its stability lifetime ?

    1 answer
    1. Product LGFR100 is supplied as lyophilized powder and should be stored at -20°C in a dry environment protected from light. Product LGFR100 can be resuspended in water.

      To re-constitute:

      remove the product from freezer
      wait until temperature rises to ambient
      add DI water or buffer to the container
      vortex and sonicate for 5 minutes to ensure the microspheres are well suspended

      It is strongly recommended to use the product immediately upon resuspension because the particles begin to degrade as soon as they are introduced into an aqueous solution. If storage of particles in suspension is required, it is recommended to store at 2-8 °C to slow the degradation.

      Helpful?

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