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重要文件

H20202

Sigma-Aldrich

4-羟基二苯甲酮

98%

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About This Item

線性公式:
HOC6H4COC6H5
CAS號碼:
分子量::
198.22
Beilstein:
777776
EC號碼:
MDL號碼:
分類程式碼代碼:
12162002
PubChem物質ID:
NACRES:
NA.23
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化驗

98%

mp

132-135 °C (lit.)

SMILES 字串

Oc1ccc(cc1)C(=O)c2ccccc2

InChI

1S/C13H10O2/c14-12-8-6-11(7-9-12)13(15)10-4-2-1-3-5-10/h1-9,14H

InChI 密鑰

NPFYZDNDJHZQKY-UHFFFAOYSA-N

基因資訊

rat ... Ar(24208)

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一般說明

4-Hydroxybenzophenone is characterized by its ability to absorb UV radiation and convert it into lower-energy radiation. This property makes it an effective photostabilizer. Its molecular structure features two aromatic rings connected by a carbonyl group, allowing for strong π-π stacking interactions, which enhance its stability and efficacy in polymer matrices. Incorporating 4-Hydroxybenzophenone into polymer matrices increases the longevity and performance of materials used in outdoor applications, such as coatings and plastics.

應用

4-Hydroxybenzophenone can be used:
  • As a photoinitiator to synthesize fluorescent triblock copolymer micelles for targeted release of cancer drugs and intracellular bioimaging. It facilitates controlled release, improving therapeutic efficacy while minimizing side effects.
  • As a photoacid catalyst for ring opening polymerization of lactones to prepare biodegradable polyesters.
  • As a precursor to synthesize functional copolymer for fabrication of nanostructured transparent metal electrodes for flexible optoelectronic devices.

象形圖

Health hazard

訊號詞

Warning

危險聲明

防範說明

危險分類

Aquatic Chronic 3 - STOT RE 2

標靶器官

Liver,Kidney

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

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Daniel Molins-Delgado et al.
The Science of the total environment, 601-602, 975-986 (2017-06-06)
The increased use of beauty and other daily use products, in particular those containing UV filters (UV-Fs) and benzotriazoles, results in their introduction in significant amounts into the aquatic environment. In this study, we aim to assess the occurrence and
Benzophenone metabolism. I. Isolation of p-hydroxybenzophenone from rat urine.
A W Stocklinski et al.
Life sciences, 26(5), 365-369 (1980-02-04)
Aneesh Karkhanis et al.
Biochemical pharmacology, 146, 188-198 (2017-09-30)
Cardiac enzymes such as cytochrome P450 2J2 (CYP2J2) metabolize arachidonic acid (AA) to cardioprotective epoxyeicosatrienoic acids (EETs), which in turn are metabolized by soluble epoxide hydrolase (sEH) to dihydroxyeicosatrienoic acids (DHETs). As EETs and less potent DHETs exhibit cardioprotective and
Francesco Barsotti et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 16(4), 527-538 (2017-01-20)
The photophysics and photochemistry of 4-hydroxybenzophenone (4HOBP) are interesting because they can give some insight into the behavior of humic material. Here we show that 4HOBP has a number of fluorescence peaks: (i) an intense one at excitation/emission wavelengths Ex/Em
S E Blanco et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 59(13), 2985-2995 (2003-10-30)
The anomalous UV spectroscopic behavior of 4-hydroxy-benzophenone and 2,4-dihydroxy-benzophenone in ethanol-acetonitrile mixtures has been investigated using theoretical and experimental methods. Band I of these compounds, associated to strong pi-->pi* transitions, suffers a blue shift when the polarity of the ethanol-acetonitrile

Questions

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    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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