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重要文件

G6600

Sigma-Aldrich

甘氨酸甲酯 盐酸盐

99%, for peptide synthesis

同義詞:

Glycine methyl ester·HCl, Methyl glycinate hydrochloride

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About This Item

線性公式:
NH2CH2COOCH3 · HCl
CAS號碼:
分子量::
125.55
Beilstein:
3593644
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.22

產品名稱

甘氨酸甲酯 盐酸盐, 99%

品質等級

化驗

99%

形狀

powder, crystals or chunks

反應適用性

reaction type: solution phase peptide synthesis

顏色

white

mp

175 °C (dec.) (lit.)

應用

peptide synthesis

SMILES 字串

Cl.COC(=O)CN

InChI

1S/C3H7NO2.ClH/c1-6-3(5)2-4;/h2,4H2,1H3;1H

InChI 密鑰

COQRGFWWJBEXRC-UHFFFAOYSA-N

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一般說明

甘氨酸甲酯盐酸盐又名甲基甘氨酸酯盐酸盐,是一种甘氨酸衍生物,用于制备氨基酸和有机化合物。

應用

甘氨酸甲酯盐酸盐可用于合成以氨基酸酯为侧链的环磷腈类物质。还可在水相中合成多肽,是一种绿色的制肽法。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

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A green protocol for peptide bond formation in WEB
M Konwar
Tetrahedron Letters, 57, 2283-2285 (2016)
The investigation of thermosensitive properties of phosphazene derivatives bearing amino acid ester groups
A Uslu
Journal of Molecular Structure, 1136, 90-99 (2017)
J M Delfino et al.
International journal of peptide and protein research, 21(4), 440-450 (1983-04-01)
The reactivity of the carboxyl groups in bovine growth hormone was studied by reaction with 1-ethyl-3(3-dimethylaminopropyl) carbodiimide in the presence of an excess of glycinemethylester. Localization in the molecule of the various kinetically distinguishable carboxyl groups was achieved. Highest reactivity
Vincenzo Santagada et al.
Journal of combinatorial chemistry, 7(4), 618-621 (2005-07-12)
An easy and convenient microwave-assisted synthesis of N-alkylated glycine methyl esters is described. Parallel and nonparallel combinatorial methods are described and compared. The described reactions are reductive alkylations of several aldehydes and glycine methyl ester in the presence of NaBH3CN.
Wenzhong Gao et al.
Organic letters, 7(19), 4241-4244 (2005-09-09)
[reaction: see text] A novel Cu(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides with acrylates has been developed. Up to 98/2 exo/endo selectivity and up to 98% enantiomeric excess have been achieved.

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