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Merck
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重要文件

938238

Sigma-Aldrich

二氧化硅

monodisperse, non-porous, 5 μm

同義詞:

二氧化硅

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About This Item

線性公式:
SiO2
CAS號碼:
分子量::
60.08
MDL號碼:
分類程式碼代碼:
12352309
暫時無法取得訂價和供貨情況

品質等級

形狀

powder

粒徑

5 μm

孔徑

non-porous

bp

2230 °C (lit.)

mp

>1600 °C (lit.)

SMILES 字串

O=[Si]=O

InChI

1S/O2Si/c1-3-2

InChI 密鑰

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

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一般說明

Our monodisperse, non-porous silica powder is a white powder composed of speherical particles, precisely engineered to achieve a monodisperse particle size of 5 µm with 99.99% purity. The microparticles do not contain any internal porosity or void spaces, making their surfaces impermeable to fluids or gases.

應用

Monodisperse, non-porous silica particles have several applications in various research areas including drug delivery, molecular imaging, and environmental remediation. Owing to their stable chemical structure, ease of surface modification, and affinity toward various biomolecules, silica microparticles are an attractive platform for bioconjugation of drugs, proteins, DNA, and other biomarkers. Consequently, non-porous silica particles and their bioconjugates are used in biomedical applications for delivering or isolating drugs, proteins, polynucleotides, and more. Bioconjugation of non-porous silica often facilitates imaging techniques including optical imaging (fluorescence and bioluminescence), magnetic resonance imaging (MRI), radionuclide imaging, computed tomography (CT), ultrasound, photoacoustic imaging, and Raman imaging.[1],[2]Apart from these applications, these monodisperse particles are also used in analytical applications, such as the stationary phase in columns for advanced, high-performance liquid chromatography.[3]

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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存取文件庫

Safety of Nonporous Silica Nanoparticles in Human Corneal Endothelial Cells
Kim J Y, et al
Scientific Reports, 7, 14566-14566 (2017)
Core-shell particles lead the way to renewing high-performance liquid chromatography
Gonzalez-Ruiz V, et al
TrAC, Trends in Analytical Chemistry, 64, 17-28 (2015)
Nonporous Silica Nanoparticles for Nanomedicine Application
Tang L, et al.
Nano Today, 8, 290-312 (2013)
Sean E Lehman et al.
Langmuir : the ACS journal of surfaces and colloids, 32(3), 731-742 (2015-12-31)
Understanding complex chemical changes that take place at nano-bio interfaces is of great concern for being able to sustainably implement nanomaterials in key applications such as drug delivery, imaging, and environmental remediation. Typical in vitro assays use cell viability as
Nano-Bio Interactions of Porous and Nonporous Silica Nanoparticles of Varied Surface Chemistry: A Structural, Kinetic, and Thermodynamic Study of Protein Adsorption from RPMI Culture Medium
Lehman S, et al.
Langmuir, 32, 731-742 (2016)

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