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Merck
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930016

Sigma-Aldrich

TissueFab® bioink 

Facile Curable GelHA, Ionic

同義詞:

3D bioprinting, Bioink, Facile Curable, Gelatin, Hyaluronic Acid

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About This Item

分類程式碼代碼:
12352201
NACRES:
NA.25
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品質等級

無菌

0.2 μm filtered

形狀

viscous liquid ((or gel))

雜質

<5 CFU/g Bioburden (Total Aerobic)
<5 CFU/g Bioburden (fungal)
<50 EU/mL Endotoxin

顏色

colorless to pale yellow

pH值

6.5-7.5

黏度

5-35 cP(37 °C)

應用

3D bioprinting

儲存溫度

2-8°C

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一般說明

Facile curable bioinks are ready-to-print bioinks formulated to crosslink without the necessity of light irradiation which can be detrimental to cell health. The bioink has a Gelatin base which as a natural protein offers excellent cytocompatibility and cell-binding motifs in order to mimic the native extracellular (ECM) microenvironment. The bioink can be crosslinked in a dilute solution of multivalent cations including TissueFab® - crosslinking solution (Cat#919926). TissueFab® - Facile curable HA bioink also contains hyaluronic acid (HA), a natural polysaccharide found ubiquitously throughout the body and cellular ECM. Cell can recognize HA through cell surface receptors CD44 and RHAMM and also degrade it through secretion of hyaluronidase. [1]

Low bioburden: Bioburden is defined as the number of contaminated organisms found in a given amount of material. We test each lot for endotoxins as well as total bioburden (aerobic and fungal) to minimize unwanted interactions. For more information: https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/microbiological-testing/pyrogen-testing/what-is-endotoxin

法律資訊

TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3


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Kevin T Dicker et al.
Acta biomaterialia, 10(4), 1558-1570 (2013-12-24)
Hyaluronan (HA) is a linear polysaccharide with disaccharide repeats of d-glucuronic acid and N-acetyl-d-glucosamine. It is evolutionarily conserved and abundantly expressed in the extracellular matrix (ECM), on the cell surface and even inside cells. Being a simple polysaccharide, HA exhibits

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