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Merck
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文件

926175

Sigma-Aldrich

Glycol Chitosan Methacrylate

Degree of methacrylation ∼45%

同義詞:

Chitosan hydrogel, Crosslinkble chitosan, Glycol chitosan, Methacrylated glycol chitosan

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About This Item

線性公式:
[C14H25NO8]n [C10H17NO6]m
分類程式碼代碼:
12352201
NACRES:
NA.23

品質等級

形狀

powder

顏色

white to light yellow, light brown

適合性

conforms to structure for NMR

儲存溫度

2-8°C

應用

Glycol chitosan is soluble at neutral pH and possesses potentially useful biological properties such as good biocompatibility accelerate wound healing, and antimicrobial properties, and it is less toxic and provide to stimulates chondrocyte growth at low concentrations. Methacrylated glycol chitosan is photo- and thermally cross-linkable and is used as a precursor for the preparation of hydrogels used in biomedical applications including drug delivery, tissue engineering, and 3D bioprinting.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Modified chitosan hydrogels as drug delivery and tissue engineering systems: present status and applications
Tapan Kumar Giri Amrit Thakur, et al.
Acta Pharmaceutica Sinica. B, Volume 2, Issue 5, 439-449 (2012)
Brian G Amsden et al.
Biomacromolecules, 8(12), 3758-3766 (2007-11-23)
Glycol chitosan is a derivative of chitosan that is soluble at neutral pH and possesses potentially useful biological properties. With the goal of obtaining biocompatible hydrogels for use as tissue engineering scaffolds or drug delivery depots, glycol chitosan was converted
K Y Lee et al.
Biomaterials, 16(16), 1211-1216 (1995-11-01)
Chitosan was selectively N-acylated with various carboxylic anhydrides, e.g., acetic, propionic, n-butyric, n-valeric and n-hexanoic anhydrides, in the presence of methanol. The degree of N-acylation of about 20-50% was obtainable without occurrence of gelation by using carboxylic anhydrides of 0.3-1.2
Evaluation of the Properties of Soluble Chitosan and Chitosan Microspheres
Carreno-Gomez, B.; Duncan, R
International Journal of Pharmaceutics, 148 (2), 231-240 (1997)
Zhilong Shi et al.
Biomaterials, 27(11), 2440-2449 (2005-12-13)
Although total joint replacement has become commonplace in recent years, bacterial infection remains a significant complication following this procedure. One approach to reduce the incidence of joint replacement infection is to add antimicrobial agents to the bone cement used to

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