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應用
Tris[(1,1,1,3,3,3-hexafluoropropan-2-yl)oxy]silane is a silylating reagent used to silylate the C-terminus of unprotected amino acids and peptides, allowing for coupling with N-silylated amino acids and peptides to form discrete peptide bonds using a one-pot method.
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
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Journal of the American Chemical Society, 143(18), 6792-6797 (2021-05-01)
A one-pot peptide bond-forming reaction has been developed using unprotected amino acids and peptides. Two different silylating reagents, HSi[OCH(CF3)2]3 and MTBSTFA, are instrumental for the successful implementation of this approach, being used for the activation and transient masking of unprotected
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