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Merck
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重要文件

915033

Sigma-Aldrich

TissueFab® bioink Bone

Vis/405 nm

同義詞:

3D Bioprinting, Bioink, GelMA, TissueFab

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About This Item

分類程式碼代碼:
12352201
NACRES:
NA.23
暫時無法取得訂價和供貨情況

描述

0.2 μm sterile filtered
suitable for 3D bioprinting applications

品質等級

形狀

gel form (viscous)

雜質

≤5 CFU/g Bioburden (Fungal)
≤5 CFU/g Bioburden (Total Aerobic)

顏色

white

pH值

6.5-7.5

應用

3D bioprinting

儲存溫度

2-8°C

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應用

TissueFab® - GelMA-Bone-Vis bioink is designed for promoting osteogenic differentiation of stem cells. It is based on Gelatin methacryloyl (GelMA) - Hydroxyapatite (HAp) hydrogel system. HAp is a highly crystalline form of calcium phosphate. HAp has a chemical similarity with the mineralized phase of bone which accounts for their excellent biocompatibility and osteoinductive and osteoconductive properties favorable for bone regeneration. HAp-containing hydrogels has been studied in literature to demonstrate their processability with different additive manufacturing approaches. Printing of cell laden structures with HAp containing bioink formulations have shown superior osteogenic properties.

包裝

Product contains 10 ml of solution packaged in glass bottle.

法律資訊

TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Nano hydroxyapatite particles promote osteogenesis in a three-dimensional bio-printing construct consisting of alginate/gelatin/hASCs
Wang X F et al.
Royal Society of Chemistry Advances, 6, 6832-6842 (2016)
Tunable hydrogel composite with two-step processing in combination with innovative hardware upgrade for cell-based threedimensional bioprinting.
Wust S. et al.
Acta Biomaterialia, 10, 630-640 (2014)
Yicong Zuo et al.
ACS applied materials & interfaces, 7(19), 10386-10394 (2015-05-01)
Modular tissue engineering holds great potential in regenerating natural complex tissues by engineering three-dimensional modular scaffolds with predefined geometry and biological characters. In modular tissue-like construction, a scaffold with an appropriate mechanical rigidity for assembling fabrication and high biocompatibility for
Xi Chen et al.
International journal of nanomedicine, 11, 4707-4718 (2016-10-04)
Periodontitis is a chronic infectious disease and is the major cause of tooth loss and other oral health issues around the world. Periodontal tissue regeneration has therefore always been the ultimate goal of dentists and researchers. Existing fabrication methods mainly
Mehdi Sadat-Shojai et al.
Materials science & engineering. C, Materials for biological applications, 49, 835-843 (2015-02-18)
The ability to encapsulate cells in three-dimensional (3D) protein-based hydrogels is potentially of benefit for tissue engineering and regenerative medicine. However, as a result of their poor mechanical strength, protein-based hydrogels have traditionally been considered for soft tissue engineering only.

文章

Bioinks enable 3D bioprinting of tissue constructs for drug screening and transplantation; select suitable bioinks for specific tissue engineering.

生物墨水可實現組織構造的 3D 生物打印,用於藥物篩選和移植;為特定組織工程選擇合適的生物墨水。

Learn how 3D bioprinting is revolutionizing drug discovery with highly-controllable cell co-culture, printable biomaterials, and its potential to simulate tissues and organs. This review paper also compares 3D bioprinting to other advanced biomimetic techniques such as organoids and organ chips.

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