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Merck
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重要文件

911518

Sigma-Aldrich

Polyester bis-MPA dendron 8 NHBoc, 1 NHS (core)

generation 3

同義詞:

Bis-MPA dendron, NHS-NHBoc dendron

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About This Item

經驗公式(希爾表示法):
C103H165N9O48
分子量::
2297.44
分類程式碼代碼:
12162002
NACRES:
NA.23
暫時無法取得訂價和供貨情況

描述

8 NHBoc, 1 NHS (core)

形狀

solid (Viscous)

分子量

generation 3

號表面基團

8

顏色

colorless to white

官能基

(NHS(core))

儲存溫度

−20°C

一般說明

  • Polymer architecture: Dendron
  • End Group Functionality: NHBoc
  • Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid

應用

Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolysable linkers presented in this type of polymers allows their degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. Therefore, this group of dendritic polymers are biocompatible and biodegradable, making them suitable for biomedical applications. The NHBoc-functionalized corona and NHS-functionalized core of this product can be readily used in bioconjugation reactions.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications
Garcia-Gallego S, et al
Progress in Polymer Science, 48, 85-110 (2015)
Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been

文章

Dendritic molecules' biomedical applications, particularly bis-MPA dendritic scaffolds, hold promise for drug delivery.

Dendrimers, polymer nanostructures, are synthesized for specific purposes by manipulating critical nanoscale design parameters (CNDPs).

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