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重要文件

795291

Sigma-Aldrich

Phenofluor 溶液

0.1 M in toluene

同義詞:

1,3-Bis(2,6-diisopropylphenyl)-2,2-difluoro-4-imidazoline

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About This Item

經驗公式(希爾表示法):
C27H36F2N2
分子量::
426.58
MDL號碼:
分類程式碼代碼:
12352101
PubChem物質ID:
NACRES:
NA.22

形狀

liquid

品質等級

濃度

0.1 M in toluene

密度

0.865 g/mL at 25 °C

官能基

fluoro

儲存溫度

2-8°C

SMILES 字串

FC1(N(C=CN1c3c(cccc3C(C)C)C(C)C)c2c(cccc2C(C)C)C(C)C)F

InChI

1S/C27H36F2N2/c1-17(2)21-11-9-12-22(18(3)4)25(21)30-15-16-31(27(30,28)29)26-23(19(5)6)13-10-14-24(26)20(7)8/h9-20H,1-8H3

InChI 密鑰

FQXXWTOSPDVNSG-UHFFFAOYSA-N

應用

Facile deoxyfluorination of phenols without preactivation (), along with highly chemoselective deoxyfluorination of highly functionalized late-stage intermediates ().

法律資訊

PhenoFluor is a trademark of SciFluor Life Sciences, LLC
PhenoFluor is a trademark of SciFluor Life Sciences, LLC

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描述
訂價

訊號詞

Danger

危險分類

Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

39.2 °F

閃點(°C)

4 °C


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Filippo Sladojevich et al.
Journal of the American Chemical Society, 135(7), 2470-2473 (2013-02-13)
An operationally simple protocol for the selective deoxyfluorination of structurally complex alcohols is presented. Several fluorinated derivatives of natural products and pharmaceuticals have been prepared to showcase the potential of the method for late-stage diversification and its functional group compatibility.
Pingping Tang et al.
Journal of the American Chemical Society, 133(30), 11482-11484 (2011-07-09)
An operationally simple ipso fluorination of phenols with a new deoxyfluorination reagent is presented.

文章

PhenoFluor enables one-step conversion of phenols to aryl fluorides, facilitating fluorination without pre-activation.

相關內容

The Ritter lab currently focuses on fluorination chemistry for late-stage functionalization of complex natural and unnatural products. PhenoFluor™ has been developed as a general reagent for the selective, predictable, direct deoxyfluorination of complex alcohols and phenols.

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