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Merck
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重要文件

78110

Sigma-Aldrich

Phe-Gly 水合物

≥98.0% (dried material)

同義詞:

L-苯丙氨酰-甘氨酸 水合物

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About This Item

線性公式:
C6H5CH2CH(NH2)CONHCH2COOH · aq
CAS號碼:
分子量::
222.24 (anhydrous basis)
Beilstein:
2218143
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
暫時無法取得訂價和供貨情況

化驗

≥98.0% (dried material)

形狀

crystals

光學活性

[α]20/D +103±3°, c = 1% in H2O

雜質

≤5% ethanol
≤5% water

mp

~260 °C (dec.)

應用

peptide synthesis

SMILES 字串

O.N[C@@H](Cc1ccccc1)C(=O)NCC(O)=O

InChI

1S/C11H14N2O3.H2O/c12-9(11(16)13-7-10(14)15)6-8-4-2-1-3-5-8;/h1-5,9H,6-7,12H2,(H,13,16)(H,14,15);1H2/t9-;/m0./s1

InChI 密鑰

QNLAQUFDXQTNOW-FVGYRXGTSA-N

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Akira Yamamoto et al.
International journal of pharmaceutics, 250(1), 119-128 (2002-12-14)
We synthesized three novel lipophilic derivatives of phenylalanyl-glycine (Phe-Gly), C4-Phe-Gly, C6-Phe-Gly and C8-Phe-Gly by chemical modification with butyric acid (C4), caproic acid (C6) and octanoic acid (C8). The effect of the acylation on the stability, permeability and accumulation of Phe-Gly
Eun-Kyung Suh et al.
Experimental cell research, 290(2), 447-456 (2003-10-22)
beta-Catenin nuclear import has been found to be independent of classical nuclear localization signal (NLS) nuclear import factors. Here, we test the hypothesis that beta-catenin interacts directly with nuclear pore proteins to mediate its own transport. We show that beta-catenin
Peptide ordering within nuclear pores in living cells.
Ronald W Holz
Biophysical journal, 104(1), 6-7 (2013-01-22)
Claire E Atkinson et al.
Biophysical journal, 104(1), 37-50 (2013-01-22)
Selective transport through the nuclear pore complex (NPC) requires nucleoporins containing natively unfolded phenylalanine-glycine (FG) domains. Several differing models for their dynamics within the pore have been proposed. We characterize the behavior of the FG nucleoporins in vivo using polarized fluorescence
S Chakrabarti et al.
Toxicology, 67(1), 15-27 (1991-03-25)
An isomeric mixture of S-[(1 and 2)-phenyl-2-hydroxyethyl]glutathione (PHEG), a glutathione conjugate of styrene, is moderately nephrotoxic. Its in vivo nephrotoxicity was characterized by significant elevations in the urinary excretion of glucose, gamma-glutamyl transpeptidase, glutamate dehydrogenase, N-acetyl-beta-D-glucosaminidase and lactic dehydrogenase 24

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