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Merck
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重要文件

775924

Sigma-Aldrich

4-Benzoylbenzoic acid N-succinimidyl ester

97%

同義詞:

4-Benzoylbenzoic acid, succinimidyl ester

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About This Item

經驗公式(希爾表示法):
C18H13NO5
CAS號碼:
分子量::
323.30
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

化驗

97%

形狀

solid

分子量

323.3

反應適用性

reagent type: cross-linking reagent

mp

207-212 °C

儲存溫度

−20°C

SMILES 字串

O=C1CCC(=O)N1OC(=O)c2ccc(cc2)C(=O)c3ccccc3

InChI

1S/C18H13NO5/c20-15-10-11-16(21)19(15)24-18(23)14-8-6-13(7-9-14)17(22)12-4-2-1-3-5-12/h1-9H,10-11H2

InChI 密鑰

MVQNJLJLEGZFGP-UHFFFAOYSA-N

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應用

A benzophenone-based photoreactive reagent shown to be useful for synthesizing photoreactive peptides and oligonucleotides.
Heterobifunctional photoreactive crosslinker. Succinimidyl ester will react with amines and the benzophenone will react non-specifically upon photoirradiation at approximately 360 nm.

象形圖

Environment

訊號詞

Warning

危險聲明

防範說明

危險分類

Aquatic Acute 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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Dan Bernardi et al.
Bioorganic & medicinal chemistry letters, 16(6), 1601-1604 (2006-01-03)
The first synthesis of an N-acylated photoactivatable analogue of reduced glutathione is described. N-(4-Benzoylbenzoyl)glutathione (8) was found to be an inhibitor and a photoaffinity probe of purified rat liver glutathione S-transferases.
Horacio F Olivo et al.
Bioorganic & medicinal chemistry letters, 20(3), 1153-1155 (2009-12-25)
We have synthesized an analog of dehydroepiandrosterone (DHEA, 1) containing both a benzophenone (BP) and a biotin (Bt) group (DHEA-BP-Bt, 8). Compound 8 was prepared by functionalization on C-17 of 1. Biocytin was reacted with 4-benzoylbenzoic acid and the product

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