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重要文件

769797

Sigma-Aldrich

Resomer® RG 755 S, Poly(D,L-lactide-co-glycolide)

ester terminated

同義詞:

Resomer® RG 755 S, PLGA

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About This Item

線性公式:
HO[C2H4O2]n[C2H2O2]mCH3
CAS號碼:
MDL號碼:
分類程式碼代碼:
12162002
NACRES:
NA.23
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品質等級

形狀

amorphous

饋電比

lactide:glycolide 75:25

黏度

0.50-0.70 dL/g

轉變溫度

Tg 48-54 °C

儲存溫度

2-8°C

SMILES 字串

O2C(C(=O)OC(C2=O)C)C.O1CC(=O)OCC1=O

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

InChI 密鑰

LCSKNASZPVZHEG-UHFFFAOYSA-N

應用

Resomer® RG 755 S, Poly(D,L-lactide-co-glycolide), a biodegradable and biocompatible aliphatic polyester, can be used in the development of nano and microparticles. It is a pharmaceutical polymer, which finds potential usage in drug delivery and gene delivery. It forms a three-dimensional porous scaffold, which can be used in tissue engineering.[1][2][3][4]

法律資訊

RESOMER is a registered trademark of Evonik Rohm GmbH

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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Development and evaluation of novel biodegradable microspheres based on poly (d, l-lactide-co-glycolide) and poly (varepsilon-caprolactone) for controlled delivery of doxycycline in the treatment of human periodontal pocket: in vitro and in vivo studies
Mundargi RC, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 119(1), 59-68 (2007)
Nano/micro technologies for delivering macromolecular therapeutics using poly (D, L-lactide-co-glycolide) and its derivatives
Mundargi RC, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 125(3), 193-209 (2008)
Nanoparticles made of fluorescence-labelled poly (L-lactide-co-glycolide): preparation, stability, and biocompatibility
Weiss B, et al.
Journal of Nanoscience and Nanotechnology, 6(9-10), 3048-3056 (2006)
In vitro degradation of three-dimensional porous poly (D, L-lactide-co-glycolide) scaffolds for tissue engineering
Wu L and Ding J
Biomaterials, 25(27), 5821-5830 (2004)

Questions

  1. SDS, sheet에는 분자량이 정보없음으로 표기되어 있는데, 혹시 분자량에 대한 정보가 업데이트되었다면, 해당 제품 분자량에 대해 알 수 있을까요?

    1 answer
    1. The molecular weight of this product is not determined on a lot specific basis. Historical data indicates an approximate molecular weight of 61.1 kDa. This may vary from lot to lot and is not considered a product specification.

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