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741957

Sigma-Aldrich

金纳米颗粒

10 nm diameter, OD 1, stabilized suspension in citrate buffer

同義詞:

Au NP, Gold Colloid

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About This Item

MDL號碼:
分類程式碼代碼:
12352302
PubChem物質ID:
NACRES:
NA.23
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形狀

nanoparticles
suspension

包含

Proprietary Surfactant as stabilizer

濃度

~6.0E+12 particles/mL

外徑

1

直徑

10 nm

λmax

515-519 nm

蛋白質二硫鍵異構酶

<0.2

儲存溫度

2-8°C

SMILES 字串

[Au]

InChI

1S/Au

InChI 密鑰

PCHJSUWPFVWCPO-UHFFFAOYSA-N

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一般說明

Gold nanoparticles (AuNPs) are quasi-dynamic materials which are commercially used for various biomedical, electrochemical and energy based applications.[1][2][3][4] AuNPs are highly stable with properties like high surface to volume ratio, high conductivity,[1] and low toxicity.[5]

應用

AuNPs can be potentially used in:
  • biomedical applications as a drug releasing agents[2]
  • cancer radiotherapy due to their excellent surface chemistry and biocompatibility[6][7]
  • electrochemical bio-sensing systems[3]

Ideal for adsorption of thiolated ligands such as oligonucleotides and polyethylene glycols. Also, due to the increased stability, these gold nanoparticles are ideal for use in physical and optical applications. Note: This product is not ideal for protein adsorption. For gold nanoparticles suitable for adsorption of proteins and other ligands for conjugate development, please see our gold nanoparticles stabilized in PBS.

This material is highly monodisperse (<12% variability in size and shape), and provides significantly improved surface reactivity. Applications include Surface Enhanced Raman Lables, Sensing/Detection, Biological Targeting, Plasmonics and Electronics.

法律資訊

Product of CytoDiagnostics, Inc.

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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存取文件庫

Gold nanoparticles for physics, chemistry and biology (2017)
Gold nanoparticles for applications in cancer radiotherapy: Mechanisms and recent advancements
Her S, et al.
Advanced Drug Delivery Reviews, 109(6), 84-101 (2017)
Various methods of gold nanoparticles (GNPs) conjugation to antibodies
Jazayeri MH, et al.
Sensing and Bio-Sensing Research, 9(6), 17-22 (2016)
Gold nanoparticles for applications in energy and environment: synthesis and characterization
Chen Y
Rare Metals, 30(1), 116-120 (2011)
Spectroscopic Study of the Interaction of Carboxyl-Modified Gold Nanoparticles with Liposomes of Different Chain Lengths and Controlled Drug Release by Layer-by-Layer Technology
Kanwa N, et al.
The Journal of Physical Chemistry B, 121(50), 11333-11343 (2017)

文章

Sustainable energy sources with high production efficiency are crucial for meeting increasing energy demand.

Steven J. Oldenburg, Ph.D. provides an overview of lateral flow diagnostic assays and discusses the use of ultra-bright reporter particles based on the unique optical properties of gold nanoshells that significantly increase the sensitivity of lateral flow immunoassays.

金 (Au) 奈米微粒具有可調式光學與電子特性,可應用於多種領域,包括光電、感測器、藥物輸送與催化。

Gold (Au) nanoparticles have tunable optical and electronic properties and are used in a number of applications including photovoltaics, sensors, drug delivery & catalysis.

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相關內容

Sustainable, environment-friendly, and clean energy sources with sufficiently high production efficiency for practical application are highly desirable to meet the energy challenge of the 21st century due to the world′s increasing energy demand.

Questions

1–10 of 18 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. How to calculate molarity of this Aunps solution?

    1 answer
    1. The molar concentration is 9.93E-09 M. This can be calculated using the weight concentration of 6.07E-02 and the molar mass of 6.11E+06.

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  4. Hello,  I want to know if I can add CTAB (cétyltriméthylammonium bromide) to this solution and expect efficient adsorption with the AuNPs without interference with the already present stabilizer ? Thanks in advance 

    1 answer
    1. There have not been previous attempts on adsorption of non-thiolated ligands to the surfactant stabilized gold nanoparticles. It is difficult to say to what extent the surfactant may influence the adsorption of CTAB to the particles.

      Please test this by transferring 1 mL of gold nanoparticle suspension into a 1.5 mL centrifuge tube, centrifuge it at 17000 x g for 25-30 minutes, remove the supernatant, and resuspend the particles in a solution of water and CTAB (<1% v/v). If the sample appears to aggregate, then this will be a sign that the reagent is not compatible with the particles.

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  5. at which concentration is the citrate buffer?

    1 answer
    1. This is a product of CytoDiagnostics, Inc. It is supplied in 0.1mg/ml citrate buffer supplemented with a proprietary stabilizing solution.

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  6. Is autoclave distilled water okay to use to dilute gold nanoparticle?

    1 answer
    1. Autoclaved, distilled water is suitable to use as a diluent for gold nanoparticles.

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  7. What diluent should be used to dilute gold nanoparticle?

    1 answer
    1. This product is prepared as a susupension in a citrate buffer. It can be further diluted with water. Avoid diluting further with buffers containing other electrolyte salts such as sodium chloride. Due to the gold nanoparticle surface charge, aggregation and color changes will occur.

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  8. Do I need to wash my gold nanoparticles?

    1 answer
    1. For most applications, our gold nanoparticles can be used without any additional washing steps. If you have a sensitive application that requires additional washing the best way to do so is by either centrifugation or filtration.

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  9. How do you attach gold nanoparticles to peptides and peptide conjugates?

    1 answer
    1. To view information on how to attach gold nanoparticles to peptides and peptide conjugates, please view the information in the reference - Rosenthal, S. J. and Wright, D. W. (Eds.). (2005), p. 91-92. NanoBiotechnology Protocols. New Jersey. Humana Press.

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  10. What is the shape of the gold nanoparticles?

    1 answer
    1. The majority (>95%) of the gold nanoparticles are spherical.

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1–10 of 18 Questions  

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