721042

3-羧基-5-硝基苯硼酸

• 同義詞: 3-Borono-5-nitrobenzoic acid, 3-羧基-5-硝基苯基硼酸, 5-羧基-3-硝基苯硼酸
• 經驗公式（希爾表示法）: C₇H₆BNO₆
• CAS號碼: 101084-81-5
• 分子量：: 210.94
• MDL號碼: MFCD00757433
• 分類程式碼代碼: 12352103
• PubChem物質ID: 329763815
• NACRES: NA.22

屬性

• 形狀: solid
• 品質等級: 100
• mp: 248-252 °C
• 官能基: carboxylic acid; nitro
• SMILES 字串: OB(O)c1cc(cc(c1)[N+]([O-])=O)C(O)=O
• InChI: 1S/C7H6BNO6/c10-7(11)4-1-5(8(12)13)3-6(2-4)9(14)15/h1-3,12-13H,(H,10,11)
• InChI 密鑰: WNIFCLWDGNHGMX-UHFFFAOYSA-N

描述

應用

3-Carboxy-5-nitrophenylboronic acid can be used as a reactant to prepare:

• Biaryl derivatives via Suzuki-Miyaura cross-coupling with aryl and heteroaryl halides via the formation of a C-C bond.[1]
• 3-Chloro-5-nitrobenzoic acid via copper-catalyzed chlorination reaction.[2]
• Aryl-clonazepam derivatives by palladium-catalyzed Suzuki Cross-coupling reaction with clonazepam in the presence of Pd as a catalyst.[3]

Reactant for:

• Copper-catalyzed chlorination
• Parallel solid-phase synthesis of azabicyclooctylidenemethylbenzamides as μ- and d-opioid agonists

Used for:

• Immobilization of glucose oxidase and acetylcholinesterase on boronic acid-activated silica surfaces

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable