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Merck
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重要文件

677280

Sigma-Aldrich

sSPhos

同義詞:

2′-二环己基膦基-2,6-二甲氧基-1,1′-联苯基-3-磺酸钠 水合物, SPhos(水溶性), [1,1′-2′-联苯基 ]-3-磺酸-(二环己基膦)-2,6-二甲氧基钠盐

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About This Item

經驗公式(希爾表示法):
C26H34NaO5PS · xH2O
CAS號碼:
分子量::
512.57 (anhydrous basis)
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:
NACRES:
NA.22
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形狀

solid

品質等級

反應適用性

reaction type: Cross Couplings
reagent type: ligand
reaction type: Suzuki-Miyaura Coupling

官能基

phosphine

SMILES 字串

O.[Na+].COc1ccc(c(OC)c1-c2ccccc2P(C3CCCCC3)C4CCCCC4)S([O-])(=O)=O

InChI

1S/C26H35O5PS.Na.H2O/c1-30-22-17-18-24(33(27,28)29)26(31-2)25(22)21-15-9-10-16-23(21)32(19-11-5-3-6-12-19)20-13-7-4-8-14-20;;/h9-10,15-20H,3-8,11-14H2,1-2H3,(H,27,28,29);;1H2/q;+1;/p-1

InChI 密鑰

MAPQBSXKBDVINV-UHFFFAOYSA-M

法律資訊

用法以美国专利 6307087 和 6395916 为准。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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General catalysts for the Suzuki-Miyaura and Sonogashira coupling reactions of aryl chlorides and for the coupling of challenging substrate combinations in water.
Kevin W Anderson et al.
Angewandte Chemie (International ed. in English), 44(38), 6173-6177 (2005-08-13)
David S Surry et al.
Angewandte Chemie (International ed. in English), 47(34), 6338-6361 (2008-07-30)
Palladium-catalyzed amination reactions of aryl halides have undergone rapid development in the last 12 years, largely driven by the implementation of new classes of ligands. Biaryl phosphanes have proven to provide especially active catalysts in this context. This Review discusses
Ruben Martin et al.
Accounts of chemical research, 41(11), 1461-1473 (2008-07-16)
The cores of many types of polymers, ligands, natural products, and pharmaceuticals contain biaryl or substituted aromatic structures, and efficient methods of synthesizing these structures are crucial to the work of a broad spectrum of organic chemists. Recently, Pd-catalyzed carbon-carbon
David S Surry et al.
Chemical science, 2(1), 27-50 (2011-01-01)
Dialkylbiaryl phosphines are a valuable class of ligand for Pd-catalyzed amination reactions and have been applied in a range of contexts. This review attempts to aid the reader in the selection of the best choice of reaction conditions and ligand

文章

Buchwald phosphine ligands for C-C, C-N, and C-O bond formation.

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