638013

4-二苯基膦基苯甲酸 2-(三甲基硅基)乙酯 溶液

0.5 M in THF

• 經驗公式（希爾表示法）: C₂₄H₂₇O₂PSi
• CAS號碼: 566190-45-2
• 分子量：: 406.53
• MDL號碼: MFCD07369722
• 分類程式碼代碼: 12352108
• PubChem物質ID: 24882904

屬性

• 反應適用性: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• 濃度: 0.5 M in THF
• 密度: 0.925 g/mL at 25 °C
• 官能基: phosphine
• SMILES 字串: C[Si](C)(C)CCOC(=O)c1ccc(cc1)P(c2ccccc2)c3ccccc3
• InChI: 1S/C24H27O2PSi/c1-28(2,3)19-18-26-24(25)20-14-16-23(17-15-20)27(21-10-6-4-7-11-21)22-12-8-5-9-13-22/h4-17H,18-19H2,1-3H3
• InChI 密鑰: QTYUNPJLGFKKRV-UHFFFAOYSA-N

描述

應用

4-Diphenylphosphanyl-benzoic acid 2-trimethylsilanyl-ethyl ester (DPPBE) was developed as an efficient alternative to triphenylphosphine in the Mitsunobu reaction since the phosphine oxide formed during the reaction can be easily removed during workup.[1]

Reagent for:

• Synthesis of alkenes
• Methylation of aldehydes
• Mitsunobu reactions

安全資訊

• 象形圖: GHS02,GHS08,GHS07
• 訊號詞: Danger
• 危險聲明: H225,H319,H335,H351
• 防範說明: P210 - P280 - P305 + P351 + P338 - P370 + P378 - P403 + P235
• 危險分類: Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 安全危害: EUH019
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: -4.0 °F - closed cup
• 閃點（°C）: -20 °C - closed cup