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Merck
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Key Documents

597201

Sigma-Aldrich

氯甲基三甲氧基硅烷

96%

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About This Item

線性公式:
(H3CO)3SiCH2Cl
CAS號碼:
分子量::
170.67
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:
NACRES:
NA.23

化驗

96%

bp

151 °C (lit.)

密度

1.132 g/mL at 25 °C (lit.)

SMILES 字串

CO[Si](CCl)(OC)OC

InChI

1S/C4H11ClO3Si/c1-6-9(4-5,7-2)8-3/h4H2,1-3H3

InChI 密鑰

FPOSCXQHGOVVPD-UHFFFAOYSA-N

一般說明

Chloromethyltrimethoxysilane (CMTMS) is a trialkoxysilane with chloromethyl as the organofunctional group having hydrophobic characteristics. Chloromethyl is the electron withdrawing group that improves the mechanical properties of the molecule. CMTMS is mainly utilized as a silane based precursor material for the preparation of surface enhancement based coatings and other silane based products.

應用

CMTMS and its colloidal solution can be used in the development of aerogels. It can also be used in surface modification of silica nanoparticle for the fabrication of in vitro anticancer drug release system.
Chloromethyltrimethoxysilane may be used in the preparation of 1-methyl-1H-benzimidazole (MBI)-modified nanoparticles.{33} Mesoporous monolithic silica gels can also be prepared from Chloromethyltrimethoxysilane. {34}

象形圖

Flame

訊號詞

Danger

危險聲明

危險分類

Flam. Liq. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

26.6 °F - closed cup

閃點(°C)

-3 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Aerogels from chloromethyltrimethoxysilane and their functionalizations
Kimura T, et al.
Langmuir, 33(48), 13841-13848 (2017)
Space-confined click reactions in hierarchically organized silica monoliths.
Keppeler M and Husing N
New. J. Chem., 35(3), 681-690 (2011)
Huan Meng et al.
Journal of the American Chemical Society, 132(36), 12690-12697 (2010-08-20)
Mesoporous silica nanoparticles (MSNP) have proven to be an extremely effective solid support for controlled drug delivery on account of the fact that their surfaces can be easily functionalized in order to control the nanopore openings. We have described recently
Zilu Li et al.
ACS nano, 9(11), 10778-10789 (2015-10-06)
We have optimized mesoporous silica nanoparticles (MSNs) functionalized with pH-sensitive nanovalves for the delivery of the broad spectrum fluoroquinolone moxifloxacin (MXF) and demonstrated its efficacy in treating Francisella tularensis infections both in vitro and in vivo. We compared two different

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