Chemical research in toxicology, 33(7), 1761-1769 (2020-06-10)
Dioscorea bulbifera L. (DBL), a traditional Chinese medicine, is a well-known herb with hepatotoxicity, and the biochemical mechanisms of the toxic action remain unknown. Diosbulbin B (DSB), a major component of DBL, can induce severer liver injury which requires cytochrome
?Transition-metal promoted reactions. 12. Molybdenum hexacarbonyl-promoted reductive cleavage of the carbon-sulfur bond?
Luh YT and Wong SC
The Journal of Organic Chemistry, 50(25), 5413-5415 (1985)
Metalloproteinase inhibitors often feature hydroxamate moieties to facilitate the chelation of metal ions in the catalytic center of target enzymes. Actinonin and matlystatins are potent metalloproteinase inhibitors that comprise rare N-hydroxy-2-pentyl-succinamic acid warheads. Here we report the identification and characterization of their biosynthetic
