563382

(R)-(+)-(3-氯苯基)环氧乙烷

• 同義詞: (R)-(+)-(3-Chlorophenyl)oxirane
• 經驗公式（希爾表示法）: C₈H₇ClO
• CAS號碼: 62600-71-9
• 分子量：: 154.59
• MDL號碼: MFCD00673317
• 分類程式碼代碼: 12352005
• PubChem物質ID: 24880095
• NACRES: NA.22

屬性

• 光學活性: [α]20/D +19°, neat
• 折射率: n20/D 1.551 (lit.)
• bp: 67-68 °C/1 mmHg (lit.)
• 密度: 1.214 g/mL at 25 °C (lit.)
• 官能基: chloro; ether
• SMILES 字串: Clc1cccc(c1)[C@@H]2CO2
• InChI: 1S/C8H7ClO/c9-7-3-1-2-6(4-7)8-5-10-8/h1-4,8H,5H2/t8-/m0/s1
• InChI 密鑰: YVMKRPGFBQGEBF-QMMMGPOBSA-N

描述

應用

(R)-(+)-3-Chlorostyrene oxide may be used as an intermediate for the synthesis of 4-aminopiperidine based human β₃-adrenergic receptor (AR) agonists.[1]

Reactant involved in:

• Diastereoselective Wadsworth-Emmons cyclopropanation for synthesis of quaternaty cyclopropyl esters
• Synthesis of phenylethanolamine derivatives as β3-adrenergic receptor agonists
• Stereoselective ring-opening for synthesis of β-aryloxy-substituted alcohols and amines
• Synthesis of Biphenyl benzoic acid derivatives as β3-adrenergic receptor agonists
• Synthesis of (S)-2-, 3-, and 4-chlorostyrene oxides with epoxide hydrolase

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H317,H319,H335
• 防範說明: P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 206.6 °F - closed cup
• 閃點（°C）: 97 °C - closed cup
• 個人防護裝備: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter