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542946

Sigma-Aldrich

(S)-(+)-4-氨基-3-羟基丁酸

97%

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About This Item

經驗公式(希爾表示法):
C4H9NO3
CAS號碼:
分子量::
119.12
MDL號碼:
分類程式碼代碼:
12352116
PubChem物質ID:
NACRES:
NA.22

化驗

97%

光學活性

[α]20/D +20.0°, c = 1.7 in H2O

mp

207-212 °C

SMILES 字串

NC[C@@H](O)CC(O)=O

InChI

1S/C4H9NO3/c5-2-3(6)1-4(7)8/h3,6H,1-2,5H2,(H,7,8)/t3-/m0/s1

InChI 密鑰

YQGDEPYYFWUPGO-VKHMYHEASA-N

一般說明

(S)-(+)-4-Amino-3-hydroxybutyric acid [(S)-GABOB] can be prepared starting from ethyl (S)-4-chloro-3-hydroxybutyrate.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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T W Stone
European journal of pharmacology, 128(1-2), 81-83 (1986-08-22)
Kynurenine and kynurenic acid are known to produce convulsions in rats and mice and it has been reported that kynurenine can displace GABA from its neuronal binding sites. The present study shows that neither kynurenine nor kynurenic acid are antagonist
T Hata et al.
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 91(3), 163-171 (1988-03-01)
SART-stressed (repeated cold-stressed) rats, experimental model animals for vagotonic-type dysautonomia, have been reported to show EEG with lower-amplitude fast waves during resting-arousal and higher-amplitude slow waves during slow-wave sleep compared to normal rats. In this report, the effects of certain
D Jordan et al.
Brain research, 268(1), 105-110 (1983-05-23)
Various doses of GABA from 0.25 to 5 mumol injected into the third ventricle decrease serum TSH rapidly. The same effect was observed with GABOB (10 mumol), the hydroxylated form of GABA. The inhibitory effect of both of these drugs
GABAergic control of anterior pituitary function in humans.
G B Melis et al.
Advances in biochemical psychopharmacology, 42, 219-242 (1986-01-01)
[Neurochemical aspects of the pharmacology of GABAergic substances].
K S Raevskiĭ
Farmakologiia i toksikologiia, 44(5), 517-529 (1981-09-01)

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