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479500

Sigma-Aldrich

1,2-双(二环己基膦基)乙烷

同義詞:

乙基二(二环己基), 1,2-乙烷二基[二环己基]膦

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About This Item

線性公式:
(C6H11)2PCH2CH2P(C6H11)2
CAS號碼:
分子量::
422.61
MDL號碼:
分類程式碼代碼:
12352001
PubChem物質ID:
NACRES:
NA.22
暫時無法取得訂價和供貨情況

形狀

solid

反應適用性

reagent type: ligand
reaction type: Decarboxylations

reagent type: ligand
reaction type: Negishi Coupling

reagent type: ligand
reaction type: Suzuki-Miyaura Coupling

mp

92.5-96.5 °C (lit.)

官能基

phosphine

SMILES 字串

C1CCC(CC1)P(CCP(C2CCCCC2)C3CCCCC3)C4CCCCC4

InChI

1S/C26H48P2/c1-5-13-23(14-6-1)27(24-15-7-2-8-16-24)21-22-28(25-17-9-3-10-18-25)26-19-11-4-12-20-26/h23-26H,1-22H2

InChI 密鑰

BOUYBUIVMHNXQB-UHFFFAOYSA-N

應用

1,2-双(二环己基膦基)乙烷可以作为配体,用于:
  • Pd催化偶氮和芳香酯脱羧基 C-H 偶联。[1]
  • 镍催化芳基氟化物与伯胺的交联反应。[2]

反应物可参与:
  • 研究聚合过程中基于配体的空间效应的作用
  • 用作亚胺加氢催化剂的亚硝酰基钼配合物的合成
  • 可转换的 C-N-结合的异构体的不可逆的热键异构化
  • 螯合将反式复合物转化为顺式复合物

铱三嵌段配合物的前体和取代基对硼酸化反应的影响

钯(II)配合物的配体催化的加氢反应

象形圖

CorrosionExclamation mark

訊號詞

Danger

危險分類

Aquatic Chronic 4 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

>230.0 °F - closed cup

閃點(°C)

> 110 °C - closed cup

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

Pd-Catalyzed Decarbonylative C- H Coupling of Azoles and Aromatic Esters.
Matsushita K, et al.
Chemistry - An Asian Journal (2018)
Nickel-catalyzed amination of aryl fluorides with primary amines.
Harada T, et al.
Chemical Communications (Cambridge, England), 54(14), 1718-1721 (2018)
Helen Larson et al.
The Journal of organic chemistry, 84(20), 13092-13103 (2019-09-25)
This manuscript details the development of the nickel-catalyzed arylation of oxazoles and benzoxazoles with aryl halides. A series of aryl, heteroaryl, and druglike electrophiles relevant to pharmaceutical applications were surveyed. The desired arylated products were obtained in synthetically useful yields

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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