推薦產品
化驗
98%
mp
72-75 °C (lit.)
官能基
amine
nitro
SMILES 字串
[O-][N+](=O)\C=C\c1ccco1
InChI
1S/C6H5NO3/c8-7(9)4-3-6-2-1-5-10-6/h1-5H/b4-3+
InChI 密鑰
WVUICGOYGDHVBH-ONEGZZNKSA-N
一般說明
2-(2-Nitrovinyl)furan (NVF) is a 2-furylethylene derivative with a potential antiprotozoal property. It forms solid inclusion complexes with cyclodextrine (CD) derivatives, 2-hydroxypropyl-β-cyclodextrin and sulfobutyl ether-β-cyclodextrin.[1] The Friedel-Crafts alkylation of naphthols with NVF in aqueous medium and catalyst-free condition has been reported.[2] The formation of Morita-Baylis-Hillman (MBH) adduct via MBH reaction of NVF with diisopropyl azodicarboxylate (DIAD) has been studied.[3]
訊號詞
Danger
危險分類
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Characterization and molecular modeling of the inclusion complexes of 2-(2-nitrovinyl) furan (G-0) with cyclodextrines.
Ruz V, et al.
International Journal of Pharmaceutics, 439(1), 275-285 (2012)
Diana Oliveira et al.
International journal of molecular sciences, 22(2) (2021-01-14)
Quorum sensing (QS) plays an essential role in the production of virulence factors, in biofilm formation and antimicrobial resistance. Consequently, inhibiting QS is being considered a promising target for antipathogenic/anti-virulence therapies. This study aims to screen 2-nitrovinylfuran derivatives structurally related
Catalyst-free Friedel-Crafts alkylation of naphthols with nitrostyrenes in the presence of water.
Halimehjani AZ, et al.
Tetrahedron Letters, 50(13), 1441-1443 (2009)
Highly efficient hydrazination of conjugated nitroalkenes via imidazole or DMAP mediated Morita-Baylis-Hillman reaction.
Dadwal M, et al.
Organic & Biomolecular Chemistry, 4(13), 2525-2528 (2006)
T O Ajiboye et al.
Microbial pathogenesis, 91, 107-114 (2015-12-02)
The involvement of reactive oxygen species and oxidative stress in 2-(2-nitrovinyl) furan mediated bacterial cell death was investigated in Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus. Time kill assay resulted in significant decrease in the optical density and colony-forming unit
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