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Merck
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重要文件

457396

Sigma-Aldrich

4-氟吲哚

97%

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About This Item

經驗公式(希爾表示法):
C8H6FN
CAS號碼:
分子量::
135.14
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
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化驗

97%

bp

90 °C/0.4 mmHg (lit.)

mp

30-32 °C (lit.)

官能基

fluoro

SMILES 字串

Fc1cccc2[nH]ccc12

InChI

1S/C8H6FN/c9-7-2-1-3-8-6(7)4-5-10-8/h1-5,10H

InChI 密鑰

ZWKIJOPJWWZLDI-UHFFFAOYSA-N

應用

  • Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
  • Reactant for preparation of antifungal agents
  • Reactant for preparation of Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for the Management of Hyperglycemia in Diabetes
  • Reactant for preparation of Potent Selective Serotonin Reuptake Inhibitors
  • Reactant for preparation of Inhibitors of HIV-1 attachment
  • Reactant for preparation of monoamine reuptake inhibitors
  • Reactant for preparation of histone deacetylase (HDAC) inhibitors
  • Reactant for preparation of inhibitors of proliferation of human breast cancer cells

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

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(Erratum)
Journal of Medicinal Chemistry, 2442-2442 null
Synthesis of (L)-4-Fluorotryptophan.
Konas DW, et al.
Synthetic Communications, 42(1), 144-152 (2012)
Journal of the Chemical Society. Perkin Transactions 1, 1765-1765 (1994)
J L Malleron et al.
Journal of medicinal chemistry, 36(9), 1194-1202 (1993-04-30)
A series of new indole derivatives (2-28) has been prepared in the search for novel 5-HT uptake inhibitors. These compounds were obtained by the condensation of N-(chloroalkyl) naphthalenesultam derivatives with the appropriate amine in presence of a base, at reflux
A synthesis of (-)-indolactam V.
Semmelhack MF and Rhee H.
Tetrahedron Letters, 34(39), 1395-1398 (1993)

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