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456128

Sigma-Aldrich

4-咪唑甲醛

98%

同義詞:

5-咪唑甲醛

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About This Item

經驗公式(希爾表示法):
C4H4N2O
CAS號碼:
分子量::
96.09
EC號碼:
MDL號碼:
分類程式碼代碼:
12352005
PubChem物質ID:
NACRES:
NA.22

化驗

98%

形狀

solid

mp

174-177 °C (lit.)

SMILES 字串

O=Cc1c[nH]cn1

InChI

1S/C4H4N2O/c7-2-4-1-5-3-6-4/h1-3H,(H,5,6)

InChI 密鑰

ZQEXIXXJFSQPNA-UHFFFAOYSA-N

一般說明

4-咪唑吡啶甲醛在硼氢化钠存在下与胺发生还原胺化反应,生成仲胺。

應用

4-咪唑甲醛可用于以下研究:
  • 新型供体-Π-受体(D-Π-A)型染料的合成。
  • 制备尿刊、十二烷基和十二烷基酯的尿刊(4-咪唑丙烯酸)。
  • 比色化学传感器的制备。
  • 手性镍(II)络合物 [Ni(II)H3L](ClO4)2 的合成,具有非手性配体 H3L(三{2-(4-咪唑基)甲基亚氨基乙基}胺)。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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Peter B Madrid et al.
Journal of combinatorial chemistry, 6(3), 437-442 (2004-05-11)
Due to growing problems with drug resistance, there is an outstanding need for new, cost-effective drugs for the treatment of malaria. The 4-aminoquinolines have provided a number of useful antimalarials, and Plasmodium falciparum, the causative organism for the most deadly
Chromene and Imidazole Based D-p-A Chemosensor Preparation and Its Anion Responsive Effects.
Son YA, et al.
Mol. Cryst. Liq. Cryst., 599(1), 16-22 (2014)
Organic Process Research & Development, 11, 206-206 (2007)
Spontaneous Resolution Induced by a Chiral Ni (II) Complex with an Achiral Tripodal Ligand#.
Sarkar S, et al.
Bull. Korean Chem. Soc., 36(3), 838-842 (2015)
Seon-Yeong Gwon et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 117, 810-813 (2013-10-03)
A new donor-π-acceptor (D-π-A) type dye was synthesized by the condensation reaction between 2-cyanomethylene-3-cyano-4,5,5-trimethyl-2,5-dihydrofuran and 4-imidazolecarboxaldehyde. The chemical structure of the dye was characterized by (1)H NMR, EA and MS. A novel chromogenic dye based on imidazole as donor unit

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