37640

2,8-喹啉二醇

≥99.0% (HPLC)

• 同義詞: 2,8-二羟基喹啉
• 經驗公式（希爾表示法）: C₉H₇NO₂
• CAS號碼: 15450-76-7
• 分子量：: 161.16
• Beilstein: 472906
• MDL號碼: MFCD00216696
• 分類程式碼代碼: 12352100
• PubChem物質ID: 57649744
• NACRES: NA.22

屬性

• 品質等級: 100
• 化驗: ≥99.0% (HPLC)
• 形狀: powder
• mp: ~290 °C (dec.)
• SMILES 字串: Oc1ccc2cccc(O)c2n1
• InChI: 1S/C9H7NO2/c11-7-3-1-2-6-4-5-8(12)10-9(6)7/h1-5,11H,(H,10,12)
• InChI 密鑰: ZXZKYYHTWHJHFT-UHFFFAOYSA-N

描述

一般說明

2,8-Quinolinediol is a quinolone derivative.[1] It has been reported as metabolite of 8-hydroxyquinoline-N-oxide in rabbits.[1] Synthesis of 2,8-quinolinediol has been reported.[1] It is reported as one of the six possible forms of 8-hydroxycarbostyril.[2] It has been detected as new UV-absorbing compound (UAC) in cow milk and its structure was elucidated using HRMS and by ¹H, ¹³C and ¹H ×¹³C NMR.[3]It is also known as 8-hydroxycarbostyril or 8-hydroxyquinolin-2(1H)-one.[4]

8-hydroxyquinolin-2(1H)-one has been reported as the tautomeric form of 2,8-quinolinediol.[2] 2,8-Quinolinediol (2,8-Dihydroxyquinoline) has been identified as one of the metabolite of quinolone formed in the culture medium of gram-negative bacteria, Pseudomonas stutzeri.[5]

應用

2,8-Quinolinediol is suitable for use as standard in a study to identify the urinary metabolites for the toxicity related processes and pathogenesis induced by doxorubicin (DOX) to rats by online and off-line LC-MS techniques.[6] It may be used as starting reagent for the preparation of two powerful β2-adrenergic receptor agonists, used for the treatment of asthma:

• Procaterol
• Indacaterol[4]

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves