359866

异腈甲基膦酸二乙酯

97%

• 同義詞: Isocyanomethylphosphonic acid diethyl ester
• 線性公式: CNCH₂P(O)(OC₂H₅)₂
• CAS號碼: 41003-94-5
• 分子量：: 177.14
• Beilstein: 4674920
• MDL號碼: MFCD00042951
• 分類程式碼代碼: 12352108
• PubChem物質ID: 24862114
• NACRES: NA.22

屬性

• 化驗: 97%
• 形狀: liquid
• 反應適用性: reaction type: C-C Bond Formation
• 折射率: n20/D 1.433 (lit.)
• bp: 84-87 °C/0.1 mmHg (lit.)
• 密度: 1.105 g/mL at 25 °C (lit.)
• 官能基: amine; isonitrile; phosphonate
• 儲存溫度: 2-8°C
• SMILES 字串: CCOP(=O)(C[N+]#[C-])OCC
• InChI: 1S/C6H12NO3P/c1-4-9-11(8,6-7-3)10-5-2/h4-6H2,1-2H3
• InChI 密鑰: ICURVXBGGDVHDT-UHFFFAOYSA-N

描述

應用

Reactant for:

• Copper-catalyzed cycloaddition reactions
• Preparation of orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase
• Synthesis of sterol analogs as antifungal agents against plant pathogens
• Asymmetric synthesis of steroidal 2,5-diketopiperazines prepared via isocyanide chemistry based on stereoselective Ugi four component condensation and subsequent cyclocondensation reactions
• The Passerini reaction

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302 + H312 + H332,H315,H319,H335
• 防範說明: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 235.4 °F - closed cup
• 閃點（°C）: 113 °C - closed cup
• 個人防護裝備: Eyeshields, Gloves, type ABEK (EN14387) respirator filter