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重要文件

338710

Sigma-Aldrich

氯甲酸(-)-1-(9-芴)乙酯 溶液

18 mM in acetone, for chiral derivatization

同義詞:

(-)-FLEC

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About This Item

經驗公式(希爾表示法):
C16H13ClO2
CAS號碼:
分子量::
272.73
MDL號碼:
分類程式碼代碼:
12352005
PubChem物質ID:
NACRES:
NA.22
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等級

for chiral derivatization

品質等級

濃度

18 mM in acetone

密度

0.79 g/mL at 25 °C

官能基

chloro

儲存溫度

2-8°C

SMILES 字串

CC(OC(Cl)=O)C1c2ccccc2-c3ccccc13

InChI

1S/C16H13ClO2/c1-10(19-16(17)18)15-13-8-4-2-6-11(13)12-7-3-5-9-14(12)15/h2-10,15H,1H3

InChI 密鑰

SFRVOKMRHPQYGE-UHFFFAOYSA-N

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一般說明

(-)-1-(9-Fluorenyl)ethyl chloroformate is mostly used as an in-capillary derivatization agent for the separation of amino acid (AA) derivatives by micellar electrokinetic chromatography (MEKC).[1]

象形圖

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訊號詞

Danger

危險分類

Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

1.4 °F

閃點(°C)

-17.0 °C

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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In-capillary derivatization with (-)-1-(9-fluorenyl) ethyl chloroformate as chiral labeling agent for the electrophoretic separation of amino acids.
Fradi I, et al.
Journal of Chromatography A, 1323, 338-347 (2014)
Radu-Cristian Moldovan et al.
Journal of chromatography. A, 1513, 1-17 (2017-08-02)
Over the last 30years, (±)-1-(9-fluorenyl)ethyl chloroformate ((±)-FLEC) was used as a chiral derivatizing agent in various analytical applications involving a wide range of endogenous, pharmaceutical and environmentally relevant molecules. This comprehensive review aims to present all the significant aspects related
Radu-Cristian Moldovan et al.
Journal of chromatography. A, 1564, 199-206 (2018-06-19)
A targeted CE-MS approach was developed for the chiral analysis of biologically relevant amino acids in artificial cerebrospinal fluid (aCSF). In order to achieve chiral resolution, the five amino acids (Ser, Asn, Asp, Gln and Glu) were derivatized with (+)-1-(9-fluorenyl)ethyl
Radu-Cristian Moldovan et al.
Journal of chromatography. A, 1590, 80-87 (2019-01-15)
D-amino acids (AA) analysis is becoming more and more relevant for metabolomics, therefore new analytical tools need to be developed. A common approach to achieve AA enantioseparation is chiral derivatization. Among the chiral derivatization reagents, (+) or (-)-1-(9-fluorenyl) ethyl chloroformate
Radu-Cristian Moldovan et al.
Journal of chromatography. A, 1467, 400-408 (2016-08-25)
In the context of bioanalytical method development, process automatization is nowadays a necessity in order to save time, improve method reliability and reduce costs. For the first time, a fully automatized micellar electrokinetic chromatography-mass spectrometry (MEKC-MS) method with in-capillary derivatization

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