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Merck
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重要文件

328324

Sigma-Aldrich

1-环戊烯羧酸

98%

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About This Item

線性公式:
C5H7CO2H
CAS號碼:
分子量::
112.13
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
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化驗

98%

mp

121-124 °C (lit.)

官能基

carboxylic acid

SMILES 字串

OC(=O)C1=CCCC1

InChI

1S/C6H8O2/c7-6(8)5-3-1-2-4-5/h3H,1-2,4H2,(H,7,8)

InChI 密鑰

PYRZPBDTPRQYKG-UHFFFAOYSA-N

一般說明

1-Cyclopentenecarboxylic acid was evaluated as a new effective anticonvulsant during Anticonvulsant Screening Program (ASP) of Antiepileptic Drug Development Program.[1]

應用

1-Cyclopentenecarboxylic acid was used in synthesis of cis-8-hexahydroindanecarboxylic acid via Diels-Alder reaction with butadiene.[2] It was also used in synthesis of isoxazole derivatives.[3]

象形圖

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訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Pengcheng P Shao et al.
Bioorganic & medicinal chemistry letters, 19(18), 5334-5338 (2009-08-18)
A series of novel isoxazole voltage gated sodium channel blockers have been synthesized and evaluated. Substitutions on the benzylic position of benzamide were investigated to determine their effect on Na(v)1.7 inhibitory potency. The spirocyclobutyl substitution had the most significant enhancement
Marzanna Strupińska et al.
Acta poloniae pharmaceutica, 66(2), 155-159 (2009-09-02)
Previously obtained picolinic acid benzylamide is a potent anticonvulsant with low neurotoxicity. In search for new effective anticonvulsants twelve new benzylamides (1-12) were synthesized and preliminary evaluated in the Anticonvulsant Screening Program (ASP) of Antiepileptic Drug Development Program (ADDP) of
Preparation of cis-Hexahydroindane-8-carboxylic Acid.
DAUBEN W, et al.
The Journal of Organic Chemistry, 26(2), 297-300 (1961)

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