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324671

Sigma-Aldrich

双(三甲基硅烷基)氨基钾

95%

同義詞:

六甲基二硅基胺基钾, 六甲基二硅氮烷 钾盐

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About This Item

線性公式:
[(CH3)3Si]2NK
CAS號碼:
分子量::
199.48
Beilstein:
4006754
MDL號碼:
分類程式碼代碼:
12352111
PubChem物質ID:
NACRES:
NA.22
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品質等級

化驗

95%

形狀

solid

密度

0.877  g/cm3 at 20 °C

SMILES 字串

C[Si](C)(C)N([K])[Si](C)(C)C

InChI

1S/C6H18NSi2.K/c1-8(2,3)7-9(4,5)6;/h1-6H3;/q-1;+1

InChI 密鑰

IUBQJLUDMLPAGT-UHFFFAOYSA-N

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一般說明

双(三甲基硅烷基)氨基钾通常简称为KHMDS,分子式为[(CH3)3Si]2NK。它常用作合成中的Bronsted碱。[1][1]

[1]KHMDS是一种碱催化剂,在烷基吡啶的烷化反应中具有高活性和选择性。[2]

應用

阴离子引发剂,用于制备聚环氧乙烷。[3]具有空间位阻的碱,用于选择性环化反应。[4]还可用于制备镧系配合物。[5][6]

特點和優勢

双(三甲基硅烷基)氨基钾(KHMDS):
  • 易于获取。
  • 对苯甲C−H键具有良好的选择性。
  • 对空间位阻C−H键具有良好的反应性。

象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1 - Skin Corr. 1B

安全危害

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

Aeilke J Kamphuis et al.
ChemSusChem, 12(15), 3635-3641 (2019-05-01)
The development of new families of active and selective single-component catalysts based on earth-abundant metal is of interest from a sustainable chemistry perspective. In this context, anionic mono(formazanate) iron(II) complexes bearing labile halide ligands, which possess both Lewis acidic and
The Journal of Organic Chemistry, 58, 6177-6177 (1993)
Synthesis of poly(ethylene oxide) with heterobifunctional reactive groups at its terminals by an anionic initiator.
M Yokoyama et al.
Bioconjugate chemistry, 3(4), 275-276 (1992-07-01)
Potassium Amide-Catalyzed Benzylic C- H Bond Addition of Alkylpyridines to Styrenes
Zhai DD, et al.
Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 57, 1650-1653 (2018)
Organometallics, 11, 2003-2003 (1992)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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