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309567

Sigma-Aldrich

(甲氧基甲基)三苯基氯化膦

97%

同義詞:

Triphenyl(methoxymethyl)phosphonium chloride

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About This Item

線性公式:
(C6H5)3P(Cl)CH2OCH3
CAS號碼:
分子量::
342.80
Beilstein:
3599844
EC號碼:
MDL號碼:
分類程式碼代碼:
12352107
PubChem物質ID:
NACRES:
NA.22
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品質等級

化驗

97%

形狀

solid

反應適用性

reaction type: C-C Bond Formation

mp

185-195 °C (dec.) (lit.)

官能基

ether
phosphine

SMILES 字串

[Cl-].COC[P+](c1ccccc1)(c2ccccc2)c3ccccc3

InChI

1S/C20H20OP.ClH/c1-21-17-22(18-11-5-2-6-12-18,19-13-7-3-8-14-19)20-15-9-4-10-16-20;/h2-16H,17H2,1H3;1H/q+1;/p-1

InChI 密鑰

SJFNDMHZXCUXSA-UHFFFAOYSA-M

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應用

(甲氧基甲基)三苯基氯化膦是 Wittig 试剂,与醛和酮反应生成取代的烯烃。这一 Wittig 反应是合成某些化合物的关键步骤,这些化合物是:
  • 抗疟药物(+)-青蒿素。[1]
  • 取代的喹啉。[2]
  • Akuammiline类生物碱鸭脚树叶碱(picrinine)。[3]
  • 7H-吡咯并[2,3-d]嘧啶衍生物,这类衍生物可作为信号转导子和转录激活子6(STAT6)抑制剂。[4]

象形圖

Exclamation markEnvironment

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

>482.0 °F

閃點(°C)

> 250 °C

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

Lot/Batch Number

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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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