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286281

Sigma-Aldrich

吲哚-3-乙酰胺

98%

同義詞:

3-吲哚乙酰胺, NSC 1969

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About This Item

經驗公式(希爾表示法):
C10H10N2O
CAS號碼:
分子量::
174.20
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
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品質等級

化驗

98%

mp

148-150 °C (lit.)

官能基

amide

SMILES 字串

NC(=O)Cc1c[nH]c2ccccc12

InChI

1S/C10H10N2O/c11-10(13)5-7-6-12-9-4-2-1-3-8(7)9/h1-4,6,12H,5H2,(H2,11,13)

InChI 密鑰

ZOAMBXDOGPRZLP-UHFFFAOYSA-N

一般說明

吲哚-3-乙酰胺是一种生长素前体[1]

應用

吲哚-3-乙酰胺用于合成 [5.5.6.6] 二氮杂环乙烷骨架[2]和吲哚-3-乙酸[3]
用于合成以下物质的反应物:
  • 蛋白激酶 C 的 PET 显像剂
  • 抗朊病毒病的潜在药物
  • 蛋白激酶C(PKC)抑制剂双吲哚基马来酰亚胺IV
  • 糖原合成酶激酶-3ß (GSK-3ß) 抑制剂
  • CaMKIId 抑制剂
  • VEGF 抑制剂
  • JAK3 抑制剂
  • NAD + 依赖性组蛋白去乙酰化酶抑制剂
  • 人脂肪细胞脂肪酸结合蛋白抑制剂
  • 细胞周期蛋白依赖性激酶抑制剂

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Stephan Pollmann et al.
Phytochemistry, 62(3), 293-300 (2003-03-07)
Acylamidohydrolases from higher plants have not been characterized or cloned so far. AtAMI1 is the first member of this enzyme family from a higher plant and was identified in the genome of Arabidopsis thaliana based on sequence homology with the
Christian O Dimkpa et al.
Applied and environmental microbiology, 78(5), 1404-1410 (2012-01-03)
The beneficial bacterium Pseudomonas chlororaphis O6 produces indole-3-acetic acid (IAA), a plant growth regulator. However, the pathway involved in IAA production in this bacterium has not been reported. In this paper we describe the involvement of the indole-3-acetamide (IAM) pathway
Rudy Maor et al.
Applied and environmental microbiology, 70(3), 1852-1854 (2004-03-10)
The plant pathogenic fungus Colletotrichum gloeosporioides f. sp. aeschynomene utilizes external tryptophan to produce indole-3-acetic acid (IAA) through the intermediate indole-3-acetamide (IAM). We studied the effects of tryptophan, IAA, and IAM on IAA biosynthesis in fungal axenic cultures and on
Elena Tsavkelova et al.
Fungal genetics and biology : FG & B, 49(1), 48-57 (2011-11-15)
The plant hormone indole-3-acetic acid (IAA) can be synthesized from tryptophan via the intermediate indole-3-acetamide (IAM). The two genes, IaaM (encoding tryptophan monooxygenase) and IaaH (encoding indole-3-acetamide hydrolase) that constitute the IAM pathway have been described in plant-associated bacteria. We
Daiana Duca et al.
Antonie van Leeuwenhoek, 106(1), 85-125 (2014-01-22)
Indole-3-acetic acid (IAA) is an important phytohormone with the capacity to control plant development in both beneficial and deleterious ways. The ability to synthesize IAA is an attribute that many bacteria including both plant growth-promoters and phytopathogens possess. There are

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    1. This product is stored at room temperature.

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