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Merck
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文件

270962

Sigma-Aldrich

双(2-氧代-3-噁唑烷基)次磷酰氯

97%

同義詞:

BOP-Cl, Phosphoric acid bis(2-oxooxazolidide) chloride

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About This Item

經驗公式(希爾表示法):
C6H8ClN2O5P
CAS號碼:
分子量::
254.56
Beilstein:
3654596
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:

化驗

97%

mp

191 °C (dec.) (lit.)

SMILES 字串

ClP(=O)(N1CCOC1=O)N2CCOC2=O

InChI

1S/C6H8ClN2O5P/c7-15(12,8-1-3-13-5(8)10)9-2-4-14-6(9)11/h1-4H2

InChI 密鑰

KLDLRDSRCMJKGM-UHFFFAOYSA-N

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應用

羧基活化和肽偶联的试剂。

取代透過

產品號碼
描述
訂價

象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Skin Corr. 1B

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


分析證明 (COA)

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T Miyazawa et al.
International journal of peptide and protein research, 40(1), 49-53 (1992-07-01)
In segment couplings by the mixed anhydride method using isobutyloxycarbonyl chloride, the use of copper(II) chloride as an additive suppressed racemization completely in the same manner as in the carbodiimide method reported previously. This was confirmed by employing a number
H T Le et al.
Bioorganic & medicinal chemistry, 4(12), 2201-2209 (1996-12-01)
BOP-Cl was found to be an efficient coupling reagent for the introduction of thiopeptide bonds on imino acid residues (Pro, Sar). Boc-amino monothioacids were coupled at moderate temperature (0 degree C-RT) with fair yields and with retained optical purity. The
D De Luca et al.
Lipids, 32(5), 559-563 (1997-05-01)
Lipophilic esters of saccharides belong to the family of nonionic surfactants widely employed in pharmaceutical and cosmetics formulations. A very simple method is presented whereby 6-O-esters of alpha- and beta-glucose can be prepared and isolated. Good results have been obtained

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