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Sigma-Aldrich

7-氨基-4-(三氟甲氧基)香豆素

≥99%

同義詞:

香豆素 151

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About This Item

經驗公式(希爾表示法):
C10H6F3NO2
CAS號碼:
分子量::
229.16
Beilstein:
4456797
EC號碼:
MDL號碼:
分類程式碼代碼:
12171500
PubChem物質ID:
NACRES:
NA.47
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品質等級

化驗

≥99%

形狀

(Powder or Crystals or Chunks)

技術

titration: suitable

mp

221-222 °C (lit.)

λmax

≤207 nm

應用

diagnostic assay manufacturing
hematology
histology

儲存溫度

room temp

SMILES 字串

Nc1ccc2c(OC(=O)C=C2C(F)(F)F)c1

InChI

1S/C10H6F3NO2/c11-10(12,13)7-4-9(15)16-8-3-5(14)1-2-6(7)8/h1-4H,14H2

InChI 密鑰

JBNOVHJXQSHGRL-UHFFFAOYSA-N

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一般說明

7-氨基-4-(三氟甲基)香豆素(AFC)是用于检测蛋白酶的一种新型荧光标记物。[1]

應用

适于用作激光染料

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

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E D Pederson et al.
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Synthesis and chemistry of 7-amino-4-(trifluoromethyl)coumarin and its amino acid and peptide derivatives
Bissell E R
The Journal of Organic Chemistry, 45, 2283?2287-2283?2287 (1980)
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Arsenolipids, especially arsenic-containing hydrocarbons (AsHC), are an emerging class of seafood originating contaminants. Here we toxicologically characterize a recently identified oxo-AsHC 332 metabolite, thioxo-AsHC 348 in cultured human liver (HepG2) cells. Compared to results of previous studies of the parent
J R Tchoupe et al.
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N-trifluoromethylcoumarinylamide derivatives of benzyloxycarbonyl-Arg-Arg, benzyloxycarbonyl-Phe-Arg and Arg are convenient chromogenic and fluorogenic substrates of cathepsin B, L and H, respectively. Benzyloxycarbonyl-Phe-Arg-N-trifluoromethylcoumarinylamide is also a highly sensitive substrate for papain.

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