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重要文件

232211

Sigma-Aldrich

4-戊炔酸

95%

同義詞:

炔丙基脲

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About This Item

線性公式:
CH≡CCH2CH2COOH
CAS號碼:
分子量::
98.10
Beilstein:
1742047
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
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品質等級

化驗

95%

形狀

solid

bp

110 °C/30 mmHg (lit.)

mp

54-57 °C (lit.)

官能基

carboxylic acid

儲存溫度

2-8°C

SMILES 字串

OC(=O)CCC#C

InChI

1S/C5H6O2/c1-2-3-4-5(6)7/h1H,3-4H2,(H,6,7)

InChI 密鑰

MLBYLEUJXUBIJJ-UHFFFAOYSA-N

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一般說明

炔丙基脲通过铜催化的分子内环化,形成烯醇内酯[1]。在Pd催化剂存在下,它能与1-溴-1-炔烃反应,产生具有生物活性的ynenol内酯[2]

應用

炔丙基脲用于:
  • 作为合成八个序列定义的模型寡聚体文库的结构单元[3]
  • 复杂多环杂环苯并[4,5]咪唑并[1,2-c]吡咯并[1,2-a]喹唑啉酮衍生物的一锅合成[4]
  • 合成各种allenenol内酯 [5(E)-(2-亚联烯基)-四氢-2-呋喃酮][5]
  • 通过 乙炔的环合复分解反应合成细胞毒性大环内酯[6]

象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Skin Corr. 1B

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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分析證明 (COA)

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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