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About This Item
經驗公式（希爾表示法）:
C12H12O4
CAS號碼:
分子量：:
220.22
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
推薦產品
等級
technical grade
形狀
powder
mp
139-144 °C (lit.)
溶解度
chloroform: soluble 5%, clear, yellow-brown
官能基
carboxylic acid
ketone
SMILES 字串
COc1ccc2C(=O)CC(CC(O)=O)c2c1
InChI
1S/C12H12O4/c1-16-8-2-3-9-10(6-8)7(4-11(9)13)5-12(14)15/h2-3,6-7H,4-5H2,1H3,(H,14,15)
InChI 密鑰
QOTZOFGBBCMWEP-UHFFFAOYSA-N
一般說明
The 5-methoxy-1-indanone-3-acetic acid derivatives are potent inhibitors of chymotrypsin-like activity of the 20S proteasome.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
R T Lum et al.
Bioorganic & medicinal chemistry letters, 8(3), 209-214 (1999-01-01)
Potent inhibitors of the 20S proteasome that contain a novel indanone head group coupled to di and tripeptides are described. These compounds are the first proteasome inhibitors have demonstrated high selectivity for the chymotrypsin-like activity of the 20S proteasome.
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