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重要文件

180947

Sigma-Aldrich

海藻酸 钠盐

powder

同義詞:

海藻酸钠, 褐藻胶

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About This Item

CAS號碼:
MDL號碼:
分類程式碼代碼:
12162002
NACRES:
NA.23
暫時無法取得訂價和供貨情況

生物源

algae (marine)

品質等級

形狀

powder

黏度

15-25 cP, 1 % in H2O

SMILES 字串

[Na+].[O-]C(=O)C1O[C@H]([C@H]([C@H]([C@@H]1O)O)O)O

InChI

1S/C6H10O7.Na/c7-1-2(8)4(5(10)11)13-6(12)3(1)9;/h1-4,6-9,12H,(H,10,11);/q;+1/p-1/t1-,2-,3-,4?,6+;/m0./s1

InChI 密鑰

MSXHSNHNTORCAW-MPGIDXPLSA-M

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一般說明

海藻酸钠是一种胶凝和无毒的阴离子多糖。 海藻酸链上的羧酸基团使其不溶于水。然而,将海藻酸转化为钠盐形式,将使其易溶于水。[1]

應用

海藻酸钠被用于:
  • 与壳聚糖组合用于制造骨组织工程的可生物降解型多孔支架。[2]
  • 研究改性两亲性藻酸盐衍生物的特性[3]
  • 利用 体外 消化模型研究藻酸盐对脂质消化速率的影响[4]
  • 制备藻酸盐水凝胶[5]
  • 作为β-半乳糖苷酶微粒的包封剂[6]

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

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存取文件庫

Zhensheng Li et al.
Biomaterials, 26(18), 3919-3928 (2005-01-01)
A biodegradable scaffold in tissue engineering serves as a temporary skeleton to accommodate and stimulate new tissue growth. Here we report on the development of a biodegradable porous scaffold made from naturally derived chitosan and alginate polymers with significantly improved
Thao Thi Thu Vu et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 100(7), 1980-1988 (2012-08-14)
Alginate hydrogels possess tunable mechanical properties that can mimic soft marrow tissue and present three-dimensional (3D) cues. This study evaluates its utility for supporting leukemic cell growth in vitro and its impact on cell survival, growth, and differentiation. Our results
Role of calcium and calcium-binding agents on the lipase digestibility of emulsified lipids using an in vitro digestion model
Hu M, et al.
Food Hydrocolloids, 24(8), 719-725 (2010)
Nora Bloise et al.
Frontiers in bioengineering and biotechnology, 8, 292-292 (2020-04-23)
Coronary artery disease is a severe ischemic condition characterized by the reduction of blood flow in the arteries of the heart that results in the dysfunction and death of cardiac tissue. Despite research over several decades on how to reduce
Eilish Broderick et al.
Journal of colloid and interface science, 298(1), 154-161 (2006-01-18)
The characterisation of a novel amphiphilic material, Alg-C4, produced from butanol linked by esterification to alginate is presented. The novel derivative retains the gelling and non-toxic properties of native alginate. FTIR spectra of Alg-C4 contained the characteristic hydroxyl and carboxyl

文章

Chitosan is a naturally occurring polysaccharide ideally suited for use in medical supplies, devices, therapeutics, and diagnostics. The unique natural characteristics of chitosan include its cationic, biocompatible, biodegradable, non-toxic, non-immunogenic, and antimicrobial properties.

Collagen molecules play a critical role in tissue architecture and strength, and in cell-matrix interactions as insoluble ligands to regulate the diverse phenotypic activities of cells.

Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.

将基于水凝胶的生物材料用于递送和募集细胞以促进体内组织再生是新生的研究热题。本文讨论了水凝胶在细胞递送和组织再生中的应用。

Questions

1–10 of 15 Questions  
  1. Is the solution made with this at a 1-3 % W/V stable if sterilely filtered and frozen or at a certain temperature does it precipitate? How long would a solution last after preparation at 4 degrees or -20 degrees or -80 degrees? No crosslinking as of yet.

    1 answer
    1. Unfortunately, no solution stability info is available for this product. The empirical result indicates that the lower w/v %, the less possibility for precipitation. The stock solution may remain stable at 4 Degrees. Storage at -20 or -80 Degrees is not recommended since phase separation may occur that reduces the stability of the solution.

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  4. what is the G/M ratio of this product? is G/M>1?

    1 answer
    1. Generally, the G/M ratio is not tested. The approximate amounts are 61% M and 39% G, resulting in an M/G ratio of 1.56. However, since this is not tested for each batch, the value cannot be guaranteed and should be treated as an approximation.

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  5. What is the species name of the seaweed from which Product No. 180947 originates?

    1 answer
    1. This product is purified from Phaeophyceae or Brown Algae.

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  6. What is the density of alginic acid sodium salt powder 180947

    1 answer
    1. Unfortunately, the density is not determined for this product.

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  7. WHAT IS THE PURITY OF THE PRODUCT NO. 180947, ALGINIC ACID SODIUM SALT?

    1 answer
    1. The purity is not analyzed on a lot-to-lot basis. This product is a mixture, not a simple compound. The ratio of mannuronic acid to guluronic acid (M/G ratio) is 1.56.

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  8. What is the structure of Product No. 180947, Alginic acid sodium salt?

    1 answer
    1. Alginic acid is a linear polymer of B-(1-->4)-D-Mannosyluronic acid and a(1-->4)-L-gulosyluronic acid residues, the relative amounts of which vary with the botanical source and the state of maturation of the plant.

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  9. Is it possible to sterilise this powder in EtOH?

    1 answer
    1. Sterilizing this product in ethanol has not been investigated. However, sources state that it possible to disinfect alginate or composite alginate hydrogels in ethanol:
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218599/

      Alternatively, solutions of Alginic acid may be sterilized by autoclaving prior to the addition of the preferred cation (required for gelation).

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  10. Why are the color and viscosity different from the same product purchased before 2022? The product with same product number which was purchased in 2023 has much more bright color and low viscosity. Was the production process changed in 2023?

    1 answer
    1. This product has the appearance specification of faint yellow to light brown. The viscosity of a 1% solution in water has a specification range of 15 - 25 cps. If the product's appearance and viscosity are outside of these ranges further information will be needed. Our Technical Service team can assist you with further troubleshooting and/or investigation. We kindly ask you to navigate to the link https://www.sigmaaldrich.com/techservice and click on "Report Product Issues" under the Products Section with all the required information so that a member of our team can reach out to you to assist further. Thank you.

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1–10 of 15 Questions  

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