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Merck
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重要文件

165190

Sigma-Aldrich

邻乙酰水杨酰氯

95%

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About This Item

線性公式:
2-(CH3CO2)C6H4COCl
CAS號碼:
分子量::
198.60
Beilstein:
880372
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
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化驗

95%

形狀

solid

折射率

n20/D 1.536 (lit.)

bp

107-110 °C/0.1 mmHg (lit.)

mp

45-49 °C (lit.)

官能基

acyl chloride
ester

SMILES 字串

CC(=O)Oc1ccccc1C(Cl)=O

InChI

1S/C9H7ClO3/c1-6(11)13-8-5-3-2-4-7(8)9(10)12/h2-5H,1H3

InChI 密鑰

DSGKWFGEUBCEIE-UHFFFAOYSA-N

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應用

  • O-Acetylsalicyloyl chloride was used in the synthesis of enantiomerically pure bidentate heteroorganic ligands built on simple achiral skeletons and containing an aziridine moiety[1].
  • It was used in the general synthesis of acetoxybenzamides[2].
  • It was used in the chemical synthesis of 2,2,6,6-tetramethyl-1-piperidinyloxy(TEMPO)-aspirin conjugate via condensation reaction with 4-hydroxy-TEMPO[3].
  • It was used as reagent in acylation of cyclobutenediones[4].

象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1 - Skin Corr. 1B

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

230.0 °F

閃點(°C)

110 °C

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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The Journal of Organic Chemistry, 58, 3543-3543 (1993)
Wilmarie Flores-Santana et al.
British journal of pharmacology, 165(4b), 1058-1067 (2011-06-11)
Inflammation and reactive oxygen species are associated with the promotion of various cancers. The use of non-steroidal anti-inflammatory drugs (NSAIDs) in cancer prevention treatments has been promising in numerous cancers. We report the evaluation of NSAIDs chemically modified by the
Aziridine ring-containing chiral ligands as highly efficient catalysts in asymmetric synthesis.
Rachwalski M, et al.
Tetrahedron Asymmetry, 24(7), 421-425 (2013)
Carlos Barea et al.
Bioorganic & medicinal chemistry letters, 21(15), 4498-4502 (2011-07-05)
Continuing with our efforts to identify new active compounds against malaria and leishmaniasis, 14 new 3-amino-1,4-di-N-oxide quinoxaline-2-carbonitrile derivatives were synthesized and evaluated for their in vitro antimalarial and antileishmanial activity against Plasmodium falciparum Colombian FCR-3 strain and Leishmania amazonensis strain

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