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146498

Sigma-Aldrich

三甲基氯化锡

同義詞:

氯三甲基锡烷

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About This Item

線性公式:
(CH3)3SnCl
CAS號碼:
分子量::
199.27
Beilstein:
3535111
EC號碼:
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:
NACRES:
NA.22
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形狀

crystals

品質等級

mp

37-39 °C (lit.)

SMILES 字串

C[Sn](C)(C)Cl

InChI

1S/3CH3.ClH.Sn/h3*1H3;1H;/q;;;;+1/p-1

InChI 密鑰

KWTSZCJMWHGPOS-UHFFFAOYSA-M

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一般說明

三甲基氯化锡是一种有机锡试剂,广泛用于将三甲基甲锡烷基转移至基质上以合成各种有机锡烷。衍生自该试剂的三甲基甲锡烷基化合物被广泛用于钯催化的Stille偶联反应。

應用

三甲基氯化锡可作为前体合成三甲基锡烷(trimethyltin hydride)、氰化物、甲醇盐、叠氮化物和锂化合物。[1]
还可用作以下反应试剂:
  • 与有机铜化合物经金属交换反应合成三甲基锡衍生物。[1]
  • 与苯甲酰氯经钯催化的偶联反应制备苯乙酮。[1]
  • 加入手性联烯钛制备旋光性炔丙基三甲基锡烷。[1]
  • 制备三甲基锡烷亲核试剂,用于经SN2反应、SRN1反应和卤族-金属交换反应形成Sn-C键。[1]
  • 在NaBH3CN和催化量AIBN存在下,与非活化二烯或三烯经自由基介导的碳环化反应合成碳环。[1]

Me3SnCl也可用作不对称烯丙基烷基化反应的路易斯酸催化剂。[1]

象形圖

Skull and crossbonesEnvironment

訊號詞

Danger

危險分類

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 2

閃點(°F)

206.6 °F - closed cup

閃點(°C)

97 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
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      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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