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Merck
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文件

112208

Sigma-Aldrich

4-硝基苯甲酰氯

98%

同義詞:

p-Nitrobenzoyl chloride

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About This Item

線性公式:
O2NC6H4COCl
CAS號碼:
分子量::
185.56
Beilstein:
473192
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

98%

形狀

solid

bp

202-205 °C/105 mmHg (lit.)

mp

71-74 °C (lit.)

SMILES 字串

[O-][N+](=O)c1ccc(cc1)C(Cl)=O

InChI

1S/C7H4ClNO3/c8-7(10)5-1-3-6(4-2-5)9(11)12/h1-4H

InChI 密鑰

SKDHHIUENRGTHK-UHFFFAOYSA-N

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一般說明

对硝基苯甲酰氯与三苯基膦盐反应,通过分子内维蒂希反应合成苯并呋喃(潜在正电子发射断层扫描 (PET) 示踪剂)。它已被用于二醇(雄烯二醇,前列腺癌的内源性增殖剂)的衍生化

應用

<ul>
<li><strong>Automated Synthesis of [11C]PiB:</strong> 4-Nitrobenzoyl chloride is utilized in the automated synthesis of [11C]PiB, a radiopharmaceutical for PET imaging of amyloid, highlighting its role in enhancing neuroimaging techniques (Singh et al., 2024).</li>
</ul>

象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 1

閃點(°F)

215.6 °F - closed cup

閃點(°C)

102 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


分析證明 (COA)

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A novel series of benzofuran derivatives as potential positron emission tomography (PET) tracers targeting amyloid plaques in Alzheimer's disease (AD) were synthesized and evaluated. The syntheses of benzofurans were successfully achieved by an intramolecular Wittig reaction between triphenylphosphonium salt and

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