跳轉至內容
Merck

AGTR1

angiotensin II receptor, type 1

同義詞:
AG2S, AGTR1A, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R
物種:
Human AGTR1 (185), naked mole-rat Agtr1 (101714068), Domestic Rabbit AGTR1 (100009164), domestic guinea pig Agtr1 (100192325), sheep AGTR1 (443107), dog AGTR1 (403836), chicken AGTR1 (396065), cow AGTR1 (281607), domestic cat AGTR1 (101082936)
UniProtKB ID:
P30556, Q13725
基因 ID:
  • Human(185) Summary: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
  • naked mole-rat(101714068) angiotensin II receptor, type 1
  • Domestic Rabbit(100009164) angiotensin II receptor, type 1
  • domestic guinea pig(100192325) angiotensin II receptor, type 1
  • sheep(443107) angiotensin II receptor, type 1
  • dog(403836) angiotensin II receptor, type 1
  • chicken(396065) angiotensin II receptor, type 1
  • cow(281607) angiotensin II receptor, type 1
  • domestic cat(101082936) angiotensin II receptor, type 1

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Small Molecule - Agonist

產品編號
描述
物種
A8846
ProteoMass™ Angiotensin II MALDI-MS Standard, vial of 10 nmol,
物種
human
A2900
[Val5]-血管紧张素II 乙酸盐 水合物, ≥95% (HPLC), powder,
物種
mouse, human, rat
A6402
[Asn1, Val5]-血管紧张素 II, ≥97% (HPLC),
物種
mouse, human, rat

Small Molecule - Antagonist

產品編號
描述
物種
T8949
替米沙坦, ≥98% (HPLC), solid,
物種
human
SML0142
缬沙坦, ≥98% (HPLC),
物種
human
1708762
缬沙坦, United States Pharmacopeia (USP) Reference Standard,
物種
human
1370462
氯沙坦钾, United States Pharmacopeia (USP) Reference Standard,
物種
human
1643419
替米沙坦, United States Pharmacopeia (USP) Reference Standard,
物種
human

Antibodies

產品編號
描述
物種活性
應用
AB15552
抗-AT1受体抗体, Chemicon®, from rabbit,
物種活性
human, mouse, rat
應用
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
SAB3500209
抗 AGTR1 兔抗, affinity isolated antibody, buffered aqueous solution,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB2100073
Anti-AGTR1 antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, guinea pig, human, mouse, rabbit, rat, sheep
應用
western blot
SAB2500038
Anti-AGTR1/AT1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
human, mouse
應用
ELISA
western blot

Small Molecule - Inhibitor

產品編號
描述
物種
C4042
卡托普利, ≥98% (HPLC), powder,
物種
human, rat
547905
2,2′:5′,2′′:5′′,2′′′-四噻吩, 96%,
物種
human, rat, mouse

Proteins

產品編號
描述
物種
HTS064M
ChemiSCREEN Human Angiotensin II Receptor, Type I Membrane Preparation, Human AT1 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
物種
human