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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Estimated to ship TODAYfromMILWAUKEE | $120.00 |
25 mg | Estimated to ship TODAYfromMILWAUKEE | $386.00 |
About This Item
Empirical Formula (Hill Notation):
C23H29N7O
CAS Number:
Molecular Weight:
419.52
NACRES:
NA.77
UNSPSC Code:
12352107
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
GLX481304 is a cell-permeable, noncytotoxic triazine-diamino compound that acts a potent, dual NOX2 and NOX4 isoform-selective inhibitor (IC50 ~ 1.25 μM) over NOX1. Does neither function as an antioxidant nor as a scavenger of reactive oxygen species (ROS). GLX481304 is shown to dose-dependently reduce ROS levels in hypoxia challenged mouse cardiomyocytes and improve contractile function in whole heart.
cell-permeable, noncytotoxic triazine-diamino compound that acts a potent, dual NOX2 and NOX4 isoform-selective inhibitor
1 of 1
This Item | |||
|---|---|---|---|
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay >95% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C |
| solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear | solubility H2O: 2 mg/mL, clear | solubility DMSO: 20 mg/mL, clear |
| color white to beige | color white to beige | color white to beige | color white to beige |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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