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P9178

Prochlorperazine dimaleate salt

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Size/SKUAvailabilityPrice
5 g

Estimated to ship onMay 26, 2026fromMILWAUKEE

$75.20

About This Item

Empirical Formula (Hill Notation):
C20H24ClN3S · 2C4H4O4
CAS Number:
Molecular Weight:
606.09
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
201-511-3
MDL number:
Form:
powder

$75.20


Estimated to ship onMay 26, 2026Details


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form

powder

Quality Segment

solubility

H2O: slightly soluble 0.3 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.3 mg/mL, methanol: soluble

originator

GlaxoSmithKline

SMILES string

OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1

InChI

1S/C20H24ClN3S.2C4H4O4/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24;2*5-3(6)1-2-4(7)8/h2-3,5-8,15H,4,9-14H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-

InChI key

DSKIOWHQLUWFLG-SPIKMXEPSA-N

Gene Information

human ... DRD2(1813)

Biochem/physiol Actions

Prochlorperazine is an anti-nausea and neuroleptic agent. It is known to cause neuropsychiatric side effects. Prochlorperazine inhibits the action of dopamine in the central nervous system. It acts as an antiemetic drug and prevents vomiting and stimulates sleep. Prochlorperazine is useful as a tranquilizer in the treatment of schizophrenia and nonpsychotic anxiety.
Phenothiazine antipsychotic; D2 dopamine receptor antagonist; antispasmodic

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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1 of 1

This Item
O111H127C4024
form

powder

form

solid

form

powder

form

powder

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

solubility

H2O: slightly soluble 0.3 mg/mL, methanol: soluble, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.3 mg/mL

solubility

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: >21 mg/mL

solubility

H2O: slightly soluble 1.5 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: >14 mg/mL, ethanol: soluble

solubility

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 29 mg/mL, H2O: insoluble, ethanol: soluble, propylene glycol: soluble

Gene Information

human ... DRD2(1813)

Gene Information

human ... DRD2(1813), HTR2A(3356), HTR2B(3357), HTR2C(3358)

Gene Information

human ... CHRM3(1131)

Gene Information

human ... BZRAP1(9256), GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), PRNP(5621), SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)
rat ... Scn2a1(24766), Scnn1a(25122), Scnn1g(24768), Slc6a1(79212)

originator

GlaxoSmithKline

originator

-

originator

-

originator

Novartis


pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Lact. - Repr. 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves



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