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Merck

1592409

USP

槲皮素

United States Pharmacopeia (USP) Reference Standard

别名:

槲皮素 二水合物, 2-(3,4-二羟基苯基)-3,5,7-三羟基-4 H -1-苯并吡喃-4-酮 二水合物, 3,3′,4′,5,7-五羟基黄酮 二水合物

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About This Item

经验公式(希尔记法):
C15H10O7 · 2H2O
CAS号:
分子量:
338.27
顏色索引編號:
75670
Beilstein:
317313
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

quercetin

製造商/商標名

USP

mp

>300 °C (lit.)

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

−20°C

SMILES 字串

OC(C(O)=C1)=CC=C1C2=C(O)C(C3=C(O)C=C(O)C=C3O2)=O

InChI

1S/C15H10O7.2H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;;/h1-5,16-19,21H;2*1H2

InChI 密鑰

GMGIWEZSKCNYSW-UHFFFAOYSA-N

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一般說明

本产品按照发行药典的发行和规定提供。支持本产品的所有信息,包括安全数据表和任何产品信息传单,都是在发行药典的授权下开发和发布的。有关更多信息和支持,请访问发行药典的网站。

應用

槲皮素USP参考标准品旨在用于USP药典规定的指定质量测试和分析。
也用于下列USP专论方法:
  • 蔓越橘果汁干提取物
  • 槐花
  • 槐花粉
  • 槐花芽
  • 槐花干提取物
  • 蔓越橘果汁干提取物胶囊
  • 芦丁

生化/生理作用

槲皮素二水合物是具有抗癌活性的黄酮类化合物。槲皮素为线粒体 ATP 酶和磷酸二酯酶抑制剂。它可抑制 PI3 激酶活性并且轻微抑制 PIP 激酶活性。槲皮素对癌细胞系具有抗增殖作用,通过 II 型雌激素受体降低癌细胞的生长,并且阻滞细胞周期晚期 G1 相中人类白血病 T 细胞。

分析報告

这些产品仅供测试和化验使用。它们不适用于人类或动物,也不能用于诊断、治疗或治愈任何类型的疾病。

其他說明

可能适用相应的销售限制。

相關產品

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 1


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This study demonstrated that 0.5% dietary rutin, ellagic acid, or curcumin markedly increased cecal succinate levels in rats fed a high-fat diet, whereas catechin, caffeic acid, and quercetin did not. Other organic acids were modestly or hardly affected by polyphenols.
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