1302214

（Z）-没药甾酮

United States Pharmacopeia (USP) Reference Standard

• 别名: (Z)-Guggulsterone, (17Z)-Pregna-4,17(20)-diene-3,16-dione, 4,17(20)-trans-Pregnadiene-3,16-dione
• 经验公式（希尔记法）: C₂₁H₂₈O₂
• CAS号: 39025-23-5
• 分子量: 312.45
• MDL號碼: MFCD01310757
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329749979
• NACRES: NA.24

属性

• 等級: pharmaceutical primary standard
• API 家族: guggul
• 製造商／商標名: USP
• 應用: pharmaceutical (small molecule)
• 格式: neat
• 儲存溫度: −20°C
• SMILES 字串: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)\C(=C\C)C(=O)C[C@@]24[H]
• InChI: 1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4+/t15-,17+,18+,20+,21-/m1/s1
• InChI 密鑰: WDXRGPWQVHZTQJ-OSJVMJFVSA-N

说明

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Guggulsterone Z USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Guggul
• Guggul Tablets
• Native Guggul Extract
• Purified Guggul Extract

生化／生理作用

(Z)-Guggulsterone is a natural product that lowers cholesterol due to its function as an antagonist ligand for the bile acid receptor. (Z)-Guggulsterone is a nuclear hormone receptor that regulates the transcription of several genes involved in cholesterol metabolism and plays a role in cholesterol level regulation. (Z)-Guggulsterone is also a selective farnesoid X receptor (FXR) modulator.

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H335
• 防範說明: P261 - P271 - P304 + P340 + P312 - P403 + P233 - P405 - P501
• 危險分類: STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable