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Merck

1176506

USP

地塞米松 21-乙酸酯

United States Pharmacopeia (USP) Reference Standard

别名:

9α-氟-16α-甲基-11β,17α,21-三羟基--1,4-孕甾二烯-3,20-二酮-21-乙酸酯, 9α-氟-16α-甲基氢化泼尼松龙-21-乙酸酯, 泼尼松龙乙酸酯

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About This Item

经验公式(希尔记法):
C24H31FO6
CAS号:
分子量:
434.50
Beilstein:
2342608
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

生物源

synthetic

等級

pharmaceutical primary standard

agency

USP

蒸汽壓力

<0.0000001 kPa ( 25 °C)

API 家族

dexamethasone

形狀

powder

包裝

pkg of 200 mg

製造商/商標名

USP

顏色

white

mp

460.4-464 °F (238—240°C)

溶解度

acetone: freely soluble
dichloromethane: slightly soluble
methanol: freely soluble
water: practically insoluble

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O

InChI

1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1

InChI 密鑰

AKUJBENLRBOFTD-RPRRAYFGSA-N

基因資訊

human ... NR3C1(2908)

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一般說明

Dexamethasone acetate (Decadron-LA) belongs to the class of long-acting glucocorticoids, commonly used as a pharmaceutical ingredient in creams, ointments, microemulsions, lotions, aerosols, etc.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Dexamethasone acetate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Betamethasone Acetate
  • Ciprofloxacin and Dexamethasone Otic Suspension
  • Dexamethasone
  • Dexamethasone Acetate
  • Dexamethasone Acetate Injectable Suspension

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

相關產品

产品编号
说明
价格

象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Repr. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

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其他客户在看

Dexamethasone Acetate
Pharmacopeia, US
United States Pharmacopeia/National Formulary, 29(5), 1815-1815 (2020)
Textbook of Veterinary Internal Medicine, 1(the), 87-92 (2009)
Development and validation of HPLC method for analysis of dexamethasone acetate in microemulsions.
Urban MCC, et al.
Brazilian Journal of Pharmaceutical Sciences , 45(1), 87-92 (2009)
Lj Zivanovic et al.
Journal of chromatography. A, 1088(1-2), 182-186 (2005-09-01)
In this paper, there was developed a sensitive, precise and accurate reversed-phase liquid chromatographic (RP-HPLC) method and validated for simultaneous determination of lidocaine hydrochloride, dexamethasone acetate (DA) and calcium dobesilate (CD) in suppositories and ointment. Also there was achieved a
Determination of dexamethasone acetate in cream by HPLC.
Garcia CV, et al.
Journal of Pharmaceutical and Biomedical Analysis, 31(3), 597-600 (2003)

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